Protein Alignment nrv3 and ATP1B4

DIOPT Version :9

• Sequence 1: NP_001260675.1
• Gene: nrv3 / 35408
• FlyBaseID: FBgn0032946
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_001135919.1
• Gene: ATP1B4 / 23439
• HGNCID: 808
• Length: 357
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 89/347 - (25%)
• Similarity: 141/347 - (40%)
• Gaps: 93/347 - (26%)

  Fly     3 DKKIGEYYAPPVKMGKWEGFK---KFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIF 64
            :|:..|....|.....|:..:   ::||:.|....|.|||.||:.|||.|..|||:|    ||:.
Human    67 EKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFYASL----AAVI 127

  Fly    65 TVFYQTL------------DNEKPKWMLDNGLIGSNPGLGFRPMPPEANVESTLVWYESSKKDNY 117
            |:...||            :..||            ||:..||.....|..     :..|:.|.:
Human   128 TLCMYTLFLTISPYIPTFTERVKP------------PGVMIRPFAHSLNFN-----FNVSEPDTW 175

  Fly   118 KYWVDETSRFLKYHTYQD-LEKQNQVNCSFEHPP-----------QDDKVCGIDFSSFSPCTA-- 168
            :::|...:.||:  .|.| |:::..|:|    ||           :|.|.|....|....|:.
Human   176 QHYVISLNGFLQ--GYNDSLQEEMNVDC----PPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLE 234

  Fly   169 DNNFGYHVARPCIFLKLNKIYNWIPEIYNDSKTLPDHMPEELKQHIKEKQSLRPNETNVVWVSCE 233
            |..|||...:|||.||:|:|..:.||:.:..|                             |||:
Human   235 DPTFGYSTGQPCILLKMNRIVGFRPELGDPVK-----------------------------VSCK 270

  Fly   234 GENPADVENIKARDYYPR-MGFPRYYFPF---KNIQGYIPPIVAVQFT-VETGVLINIECKAWAR 293
            .:. .|..:|::..|||. ..|...|:|:   .....|..|:||:.|| |.....:.::|:...:
Human   271 VQR-GDENDIRSISYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGK 334

  Fly   294 NINHDRSDRR--GSVHFELMVD 313
            .:.:|..:.|  |.|.|.|.::
Human   335 GVINDVINDRFVGRVIFTLNIE 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv3	NP_001260675.1	Na_K-ATPase	20..307	CDD:395224	82/322 (25%)
ATP1B4	NP_001135919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..80		3/12 (25%)
		Na_K-ATPase	82..351	CDD:306737	84/325 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4783
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4506
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm8622
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.980