Protein Alignment CG8665 and ALD5

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_010996.2
• Gene: ALD5 / 856804
• SGDID: S000000875
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 217/480 - (45%)
• Similarity: 312/480 - (65%)
• Gaps: 9/480 - (1%)

  Fly   432 PTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQITPRQRG 496
            ||.||||||||.::.::|.:::||:|||.:..|..|...|||:||.||..||...|..:.|..|.
Yeast    43 PTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRA 107

  Fly   497 QLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPAR 561
            :.:.|||||:|:::|.||.|||:|:|.....| :..|.:..:..|...||.|||.||.|...
Yeast   108 KALFNLADLVEKHQETLAAIESMDNGKSLFCA-RGDVALVSKYLRSCGGWADKIYGNVIDTG--- 168

  Fly   562 PNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRA 626
             .|..|::.|||:||||.|.|||:||:|.|||:...:|.|||.::|||:|.||:||..::|...|
Yeast   169 -KNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEA 232

  Fly   627 GFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLI 691
            |.|.||:|:|||.|...|:.::.|..|:|:.|||||..|:||||..||: :||.:||||||||.|
Yeast   233 GIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADT-VKKVTLELGGKSPNI 296

  Fly   692 IFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAH 756
            :|||.|:|||||:....:|:|.||.|.|..|::::|.:::|.::::.....::.:|||.|.....
Yeast   297 VFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQ 361

  Fly   757 GPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIM 821
            |.|.......|:|::......|||:||.||.| ...||||..||||.:|.:||.|.:||.||||:
Yeast   362 GAQTSDKQLHKILDYVDVAKSEGARLVTGGAR-HGSKGYFVKPTVFADVKEDMRIVKEEVFGPIV 425

  Fly   822 IISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGF 886
            .:|||  |.:|.::..||.::||||:|:.|.||.||::.:.|::||||::|.||......|||||
Yeast   426 TVSKF--STVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGF 488

  Fly   887 KQSGYGKDLGQEALNEYLKTKCVTV 911
            .|||.|:::|:.||:.|.:||.|.:
Yeast   489 GQSGIGREMGEAALSNYTQTKSVRI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	217/480 (45%)
ALD5	NP_010996.2	ALDH_F1-2_Ald2-like	41..513	CDD:143410	217/478 (45%)