Protein Alignment CG8665 and Aldh3a2

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_006246591.1
• Gene: Aldh3a2 / 65183
• RGDID: 61866
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 130/466 - (27%)
• Similarity: 216/466 - (46%)
• Gaps: 59/466 - (12%)

  Fly   461 LCKVACASATDVDKAVRAAHSAFYGSWRQITPRQRGQLMLNLADLM-ERNKEELATIESVDSGAV 524
            |.:.|.:|...:::.|:.....| .|.|....|.|.|.:..|..:: ||.|:.||.|.:..|.:
  Rat    67 LPRSAFSSGPAMERQVQRLRQTF-RSGRSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKS- 129

  Fly   525 YTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARP--NNVLT-----FTRKEPIGVCGLITP 582
             .|...:|..::|      .|..|.:.||...:..|||  .|:||     :.:.||:||..:|..
  Rat   130 -ELNAYSHEVITI------LGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPEPLGVVLIIGA 187

  Fly   583 WNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVIN-----VLPGKGSD 642
            ||||.::....:...|||||..::||::....||...|||.      |..::     ::.|...:
  Rat   188 WNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELL------PQYLDQDLYMIVNGGVEE 246

  Fly   643 AGQAVA---DHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKH 704
            ..:.:.   ||.|     :||:|.:||.:|::.| .:|...:||||||||..|..|||:|.|.:.
  Rat   247 TTELLRQRFDHIL-----YTGNTAVGKIVMEAAA-KHLTPVTLELGGKSPCYIDRDCDLDVACRR 305

  Fly   705 GMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHK----AHF 765
            .....:.|.|:.|||...:..|..:.|:.:::: ||    |:.|....:....|...:    .||
  Rat   306 ITWGKYMNCGQTCIAPDYILCEASLQDQIVQKI-KD----TVKDFYGENVKASPDYERIINLRHF 365

  Fly   766 DKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIM-IISKFNGS 829
            .::     :.:.||.|:.:||  ..:....:..||:.|:|..:..:.|||.||||: |:|..|
  Rat   366 KRI-----KSLLEGQKIAFGG--ETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKN-- 421

  Fly   830 DIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVN--VYNKTDVAAPFGGFKQSGYG 892
             ::..:...|..|..||..:|:.:........|...:|.|..|  :.:.|..:.||||...||.|
  Rat   422 -VEEAINFINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMG 485

  Fly   893 KDLGQEALNEY 903
            ...|:.:.:.:
  Rat   486 AYHGKYSFDTF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	130/466 (28%)
Aldh3a2	XP_006246591.1	ALDH_F3AB	82..521	CDD:143450	127/451 (28%)