Protein Alignment CG8665 and Aldh1l1

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_063142735.1
• Gene: Aldh1l1 / 64392
• RGDID: 621294
• Length: 921
• Species: Rattus norvegicus
• Alignment Length: 921
• Identity: 526/921 - (57%)
• Similarity: 668/921 - (72%)
• Gaps: 33/921 - (3%)

  Fly     5 MRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGV 69
            |:||:||||.|..:|. ..|.:...::|||||||||..:.|.|...|....:|||||..||.:|.
  Rat     1 MKIAVIGQSLFGQEVY-CQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQ 64

  Fly    70 ALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEV 134
            |||||:.:|:::||.|||||||||||||||||....|||.||||:||||||||||:||||.||:.
  Rat    65 ALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKK 129

  Fly   135 AGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQP 199
            .||:|||||||||||.|||.::..|...||:.|:|.|||:|||:|.|..||.::|.||||:..|.
  Rat   130 GGFTIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRCPQS 194

  Fly   200 EVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTE---EQIRLFGAHLY 261
            |.||||: .:.|.|...||....||.|.|::||.|.||||        .||   :::..|.:.|.
  Rat   195 EEGATYE-GIQKKETAKINWDQPAEAIHNWIRGNDKVPGA--------WTEACGQKLTFFNSTLN 250

  Fly   262 SAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIK-RGTKVISASEWFKQAEDQSIT 325
            ::|..:.|:.|.:.|..:...:...||::.|.|...:.::.|: ...|::.||::||.:....:
  Rat   251 TSGLSTQGEALPIPGAHRPGVVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSASSDL- 314

  Fly   326 DFSEDELVKRSLLAGIWKAILKE--DVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVF 387
            :.:|.||.....:...|..||..  :||.|||||.|||.|:|||||||||||..| :.|:||.|:
  Rat   315 ELTEAELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVY 379

  Fly   388 MAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKA-NKREIRVPTQLFINGEFVDAEAQRTLE 451
            ||..|..|..||||.||    |..::......:..|| ||..:::|.||||.|||||||..:|..
  Rat   380 MATTFRGFIQLLVRKLR----GEDDESECVINYVEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYN 440

  Fly   452 IVNPTNEEVLCKVACASATDVDKAVRAAHSAF-YGSWRQITPRQRGQLMLNLADLMERNKEELAT 515
            .:|||:..|:|:|:.|..:||||||.||..|| .|.|.:|..|.||:|:..|||:||:::|||||
  Rat   441 TINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADVMEQHQEELAT 505

  Fly   516 IESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLI 580
            ||::|:||||||||||||||||:.:||||||||||||.|||:|.||||..||.|:|||:||||::
  Rat   506 IEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIV 570

  Fly   581 TPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQ 645
            .||||||||||||.|||:|||||.:|||||..|||||||||||::||.|.||:|:|||.||..||
  Rat   571 IPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQ 635

  Fly   646 AVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVF 710
            .::||..|||:||||||.:|||||||||.||:||.|||||||||||||||||::|||:.||||||
  Rat   636 RLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVF 700

  Fly   711 FNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRG 775
            ||||||||||||||||:.||::|:::|::::..|.||:||:|.|.||||||:||..||:|:|:||
  Rat   701 FNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRG 765

  Fly   776 VDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANR 840
            |.|||.||.||.:||. .|:||.|||||:|.|.|:||:|||||||||||:|...|:|:::.|||.
  Rat   766 VKEGATLVCGGNQVPR-PGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANA 829

  Fly   841 TEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYL- 904
            ||:||||||||:||.|||..:|:::|||||:|.|||||||||||||||||:|||||.:.|:..|
  Rat   830 TEFGLASGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGNQTLSGRLL 894

  Fly   905 -------KTKC 908
                   .|||
  Rat   895 SSKHLSRATKC 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886	120/201 (60%)
		FDH_Hydrolase_C	212..316	CDD:187731	30/107 (28%)
		PP-binding	336..394	CDD:425746	33/60 (55%)
		ALDH_F1L_FTFDH	428..913	CDD:143458	325/490 (66%)
Aldh1l1	XP_063142735.1	None