Protein Alignment CG8665 and aldh5a1

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_009290813.1
• Gene: aldh5a1 / 565235
• ZFINID: ZDB-GENE-070228-2
• Length: 522
• Species: Danio rerio
• Alignment Length: 500
• Identity: 172/500 - (34%)
• Similarity: 272/500 - (54%)
• Gaps: 32/500 - (6%)

  Fly   415 LDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAA 479
            ||..|..|:         |:.||:|.:|.|.:  :..:.:|...|.:.||:.....:...||.||
Zfish    40 LDVSASLLR---------TEGFIDGRWVSAAS--SFPVFDPATGEEIAKVSDCGTKEAQDAVNAA 93

  Fly   480 HSAFYGSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVG---MSIEAWR 541
            |.|| ..|:..|.::|..|:....||:.:::|:||.:.:.:.|.    .:|..:|   .|.....
Zfish    94 HKAF-NLWKNHTAKERSILLRKWFDLIIQHREDLAKLITAECGK----PMKESLGEMTYSASFLE 153

  Fly   542 YFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLI 606
            :|:....::.|:.:.. ||:...:|..  |:|:||..:|||||:|..|::.|:.|.:|.|.|.::
Zfish   154 WFSEEARRVYGDIVAA-PAKDRKILIL--KQPVGVASIITPWNFPSAMITRKVGAALAVGCTVVV 215

  Fly   607 KPAQTCPLTALKFAELTVRAGFPPGVINVLP---GKGSDAGQAVADHELVRKLGFTGSTPIGKHI 668
            |||:..||:||..|||:|:||.|.||.||:|   .|....|:.:....||.|:.|||||..||.:
Zfish   216 KPAEDTPLSALALAELSVQAGIPAGVFNVVPCSREKTPAVGELLCTDPLVAKISFTGSTATGKVL 280

  Fly   669 MKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEF 733
            ::..| ..:|:.|:||||.:|.|:|...|:||||...|.|.|.|.|:.|:.:.|..|:..|||.|
Zfish   281 LRHAA-GTVKRVSMELGGHAPFIVFDSADVDKAVAGAMGSKFRNSGQTCVCSNRFLVQTGIHDAF 344

  Fly   734 IRRVLKDL-RTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFF 797
            :.::.|.: ..:.:|...:.||..||..:....:|:.:.....||.||.:|.||.|   |:|.|.
Zfish   345 VEKLAKTMDAELKLGHGSEPSTTQGPLINSRAAEKVEKQVADAVDHGAVVVRGGKR---LQGSFM 406

  Fly   798 TPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFAD 862
            .||:.:|||.||...:||:|||::.:.|||..  ...:..||.:..|||...:::|:.:....|:
Zfish   407 EPTLLSNVTSDMLCMREETFGPLIPVVKFNTE--QEALAIANASPVGLAGYFYSRDMAQIWRVAE 469

  Fly   863 RIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTK 907
            ::|.|.|.||....:...|||||.||||.|::.....::|||:.|
Zfish   470 QMEVGMVGVNEGMISTTEAPFGGIKQSGLGREGSIYGVDEYLEIK 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	167/486 (34%)
aldh5a1	XP_009290813.1	ALDH_F5_SSADH_GabD	66..518	CDD:143421	161/462 (35%)