Protein Alignment CG8665 and Aldh7A1

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 474
• Identity: 131/474 - (27%)
• Similarity: 227/474 - (47%)
• Gaps: 30/474 - (6%)

  Fly   454 NPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQITPRQRGQLMLNLADLMERNKEELATIES 518
            :|...:.:.||...:..:::..:..|..| |..|||:....||:::..:.|.:.:.||.|..:.|
  Fly    68 DPGTGQPIAKVRQGNVQELEHTIGLAVEA-YKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVS 131

  Fly   519 VDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPAR-PNNVLTFTRKEPIGVCGLITP 582
            ::.|.:|:.. :..|...|:...|..|......|..|  |..| .:::|...|  |:||.|:|:.
  Fly   132 LEVGKIYSEG-QGEVQEFIDICDYAVGLSRIYSGQLI--NSERADHSILEAWR--PLGVVGVISA 191

  Fly   583 WNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALK----FAELTVRAGFPPGVINVLPGKGSDA 643
            :|:|..:..|..|..:..||:.|.|.|.:.||.::.    .||:..|...|| |:.:..| |:|.
  Fly   192 YNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDV 254

  Fly   644 GQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSS 708
            ||.:...:.|..:.||||...|:.:... ......|..|||||.:.|||....::..|:...:..
  Fly   255 GQTLVADKRVNLVSFTGSCQTGRDVGVE-VQRRFGKVILELGGNNALIIDESANVKMALDAALFG 318

  Fly   709 VFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTM--TIGDPLDRSTAHGPQNHKAHFDKLLEF 771
            .....|:.|....|:.|.:::||:|::.::...:.:  .||..|:..|..||    .|..:.:|.
  Fly   319 CIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGP----VHTQQNVEN 379

  Fly   772 CRRGVDE----GAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDID 832
            .:..:.|    |..:.:|| .|....|::..|||.|.:..|..:...|:|.||:.|.|  ..::|
  Fly   380 YKAAIAEAKSLGGTVAFGG-NVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILK--AKNVD 441

  Fly   833 SLMQRANRTEYGLASGVFTKDIGKALNF--ADRIEAGTVFVN-VYNKTDVAAPFGGFKQSGYGKD 894
            ..::..|..|.||:|.:||::||:|..:  |...:.|.|.:| ..|..::...|||.|.:|.|::
  Fly   442 QAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRE 506

  Fly   895 LGQEALNEYLKTKCVTVEY 913
            .|.:|..:|.|...:||.:
  Fly   507 SGSDAWKQYCKRATITVNH 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	131/472 (28%)
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	131/474 (28%)