Protein Alignment CG8665 and Aldh

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 234/524 - (44%)
• Similarity: 339/524 - (64%)
• Gaps: 20/524 - (3%)

  Fly   399 LVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVP--------TQLFINGEFVDAEAQRTLEIVNP 455
            ::|.|:.| |...:|..:|.|..  ||...:..|        |.:|||.|:..:::.:..|.:||
  Fly     1 MLRVLKTG-ALLRSQAKNFAAAV--ANYSSLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINP 62

  Fly   456 TNEEVLCKVACASATDVDKAVRAAHSAF-YGS-WRQITPRQRGQLMLNLADLMERNKEELATIES 518
            |..||:.::.||...|:|.||:||.:|| .|| ||::...:||:|:..|||||||::..||::|:
  Fly    63 TTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLET 127

  Fly   519 VDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPW 583
            :|:|..|:::....:..:|:..||||||.||..|.|||::    .:..|:||.||:||||.|.||
  Fly   128 LDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMD----GDFFTYTRHEPVGVCGQIIPW 188

  Fly   584 NYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVA 648
            |:|::|::||:...:|.|||.::|||:...||||..|:|...||||.||:||:||.|: ||.|:|
  Fly   189 NFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALA 252

  Fly   649 DHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNK 713
            :|..|.|:.|||||.:||.|..:..::|||:.:||||||||.||.:|.|||.||:.....:|||.
  Fly   253 NHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNM 317

  Fly   714 GENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDE 778
            |:.|.|..|.||||:|:|||:.|..:..:..|:|:|.|.:|..|||.::...:|:|...:.|..:
  Fly   318 GQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQ 382

  Fly   779 GAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEY 843
            |||||.||.|...|.|||..||||.:|.|||.||:||.|||:..:.:|  ..:|.:::|||.:||
  Fly   383 GAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRF--KKLDEVIERANNSEY 445

  Fly   844 GLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKC 908
            |||:.|||||:.||......:.||||:||.||.....|||||:|.||:|::.|:.||:.|.:.|.
  Fly   446 GLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKS 510

  Fly   909 VTVE 912
            |.|:
  Fly   511 VIVK 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	225/495 (45%)
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	223/486 (46%)