DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8665 and P5CDh2

DIOPT Version :10

Sequence 1:NP_610107.1 Gene:CG8665 / 35407 FlyBaseID:FBgn0032945 Length:913 Species:Drosophila melanogaster
Sequence 2:NP_788705.1 Gene:P5CDh2 / 32625 FlyBaseID:FBgn0053092 Length:614 Species:Drosophila melanogaster


Alignment Length:641 Identity:139/641 - (21%)
Similarity:234/641 - (36%) Gaps:182/641 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   358 ASGAGSMDVVRLVE---EVKEAF--DVPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDF 417
            ||..|.:..||...   |:.|.|  |..:.||::..   ::|           ||    .::.:.
  Fly    22 ASVKGGLVSVRSTSKRPELSEHFTLDEMVANEKLLQ---YDE-----------GS----KERTEL 68

  Fly   418 EAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTN-----------EEVLCKVACASATD 471
            |...|....|...||  :.|||:  :.:|:...:.|.|.:           ..||.::|      
  Fly    69 ETALLGVLNRVEHVP--IVINGQ--EFQAKEDFQQVLPYDIQQPIAHYGHAHRVLIQMA------ 123

  Fly   472 VDKAVRAAHSAFYGSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAV-YTLALKTHVGM 535
            :||:|.|     ...|.::....|       .|:.||....:|       |.. |.:...|.:| 
  Fly   124 IDKSVEA-----QVKWDKVRLSDR-------IDIWERAAMLIA-------GRYRYNIIAATMLG- 168

  Fly   536 SIEAWRYFAGWCDKIQGNTI--------------PVNPARPNNVLTFTRK----EPI-------- 574
                           ||.|:              .:||       .|.|:    |||        
  Fly   169 ---------------QGKTLRQAEMDVAELVDFMRINP-------VFLRELANYEPIRDIQNNCR 211

  Fly   575 ---------GVCGLITPWNYPLMMLSWKMAACIA-----AGNTCLIKPAQTCPLTALKFAELTVR 625
                     |....|:|:|:.      .:||.:|     .||:.:.||:.:..|:.....:....
  Fly   212 NSMRLRGLSGFVAAISPFNFT------GIAANLAYTPALMGNSVIWKPSDSAILSNYFVFKALRE 270

  Fly   626 AGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADS-----NLKKCSLELG 685
            ||.|.||:|.:|.:.:.....|..|..:..:.|||::.:.|.:.:..|.:     |..:...|.|
  Fly   271 AGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGG 335

  Fly   686 GKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDL-------RT 743
            ||:...:.:..:.:.||...:.:.|...|:.|.:...|:|.:.:....||..|.::       :.
  Fly   336 GKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQD 400

  Fly   744 MTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAK---LVYGGCRVPNLKGYFFTPTVFTNV 805
            .|..|    |......|.:| :|::..:.|. :|:...   ||.|.|  ...:||:..|||....
  Fly   401 ATYCD----SFCSAVINRRA-YDRIYMWLRY-IDQSPSCQILVGGSC--DKRRGYYVDPTVVLVK 457

  Fly   806 TDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNF------ADRI 864
            ..|..|.:||...||:.:..:....:...|::..:..:||...||.:|    .||      |.|:
  Fly   458 DLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQD----QNFIEEAYDAFRV 518

  Fly   865 EAGTVFVNVYNKTD----VAAPFGGFKQSGYGKDLG----------QEALNEYLKT 906
            ..|.  :||.:|:.    ...|||....:|....||          .:.:.|..||
  Fly   519 NVGN--LNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLRWTSPQVIKESYKT 572

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8665NP_610107.1 FMT_core 5..207 CDD:444886
FDH_Hydrolase_C 212..316 CDD:187731
PP-binding 336..394 CDD:425746 11/40 (28%)
ALDH_F1L_FTFDH 428..913 CDD:143458 122/566 (22%)
P5CDh2NP_788705.1 ALDH-SF 50..570 CDD:448367 128/609 (21%)
Blue background indicates that the domain is not in the aligned region.

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