Protein Alignment CG8665 and ALDH3B2

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001026786.3
• Gene: ALDH3B2 / 222
• HGNCID: 411
• Length: 385
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 92/342 - (26%)
• Similarity: 154/342 - (45%)
• Gaps: 36/342 - (10%)

  Fly   568 FTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGV 632
            |..|||.|:..:|.||||||.:....:...:|||:..::||::....|....||:.      |..
Human    18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVL------PQY 76

  Fly   633 IN-----VLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLII 692
            ::     |:.|...:.|| :.:|:| ..:.||||..:||.:| :.|..:|...:||||||:|..:
Human    77 LDQSCFAVVLGGPQETGQ-LLEHKL-DYIFFTGSPRVGKIVM-TAATKHLTPVTLELGGKNPCYV 138

  Fly   693 FADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHG 757
            ..:||............:||.|:.|:|...:.....:.:..: ..|:...|...||....|...|
Human   139 DDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL-PALQSTITRFYGDDPQSSPNLG 202

  Fly   758 PQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMI 822
            ...::..|.:|     |.:...:::..||  ..|....:..|||..:|.:...:.|||.||||:.
Human   203 HIINQKQFQRL-----RALLGCSRVAIGG--QSNESDRYIAPTVLVDVQETEPVMQEEIFGPILP 260

  Fly   823 ISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGT-------VFVNVYNKTDVA 880
            |  .|...:|..::..||.|..||...|:..........:|..:|:       .::::     ::
Human   261 I--VNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISL-----LS 318

  Fly   881 APFGGFKQSGYGKDLGQ 897
            .||||...||.|:..|:
Human   319 VPFGGVGHSGMGRYHGK 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	92/342 (27%)
ALDH3B2	NP_001026786.3	ALDH-SF	1..366	CDD:448367	92/342 (27%)