Protein Alignment CG8665 and Aldh7A1

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_316857.3
• Gene: Aldh7A1 / 1277397
• VectorBaseID: AGAMI1_003438
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 493
• Identity: 131/493 - (26%)
• Similarity: 240/493 - (48%)
• Gaps: 37/493 - (7%)

  Fly   438 NGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQITPRQRGQLMLNL 502
            |||:|...|.: ::.::|.:..|:.:||..|..|:::.:.|..:| |..|::|....||.::..:
Mosquito    55 NGEWVAGTAGK-VQSIDPASGRVIAEVATGSEQDLERCLTAGVAA-YQEWKKIPAPLRGDVIRQI 117

  Fly   503 ADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPA-----RP 562
            .|.:.:.:|.|..:.:::.|.:    |...||...|    |...||...|.:.....|     ||
Mosquito   118 GDELRKYREPLGKLVALEMGKI----LPEGVGEVQE----FVDICDYAVGLSRMFGGAIFPSERP 174

  Fly   563 NNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTV--- 624
            .:.: ..:..|:|:.|:|:.:|:|..:..|..|..:..|||.|.|.|.:..|.::...::..
Mosquito   175 QHTI-LEKWNPLGLVGVISAFNFPCAVFGWNAAIALTVGNTVLWKGAPSTSLVSVATTKIVTDVI 238

  Fly   625 -RAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHI---MKSCADSNLKKCSLELG 685
             |...|| ::.:..| |.|.|:.:...|.:|.:.|||||.:|:.:   |:    ....:|.||||
Mosquito   239 KRNKLPP-IVTLCQG-GEDVGKRMVSDERIRLMSFTGSTAVGRTVGIEMQ----RRFGRCLLELG 297

  Fly   686 GKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTM--TIGD 748
            |.:.|||..|...:.|:...........|:.|....||.:..:::|.||.:::|...::  .:|.
Mosquito   298 GNNALIINEDAPQEMALDAAFFGCIGTAGQRCTTTRRLIIHAKLYDSFIAKLVKRYASLLKRVGH 362

  Fly   749 PLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQ 813
            |||.:|.:||.:::...|..|:..:..|..|.|:..|| :|.:..|:|..||:.:|:..|..:.:
Mosquito   363 PLDSATLYGPVHNQQAVDNYLQTVQEAVALGGKVECGG-KVIDRAGFFVEPTIISNLPHDAPVVK 426

  Fly   814 EESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNK-- 876
            .|:|.||:.:  |..|::...:...|..:.||:|.:||.:|..|..:.....:....||:...
Mosquito   427 RETFAPIVYV--FKASNLQEAISWNNEVDQGLSSSLFTNNIQSAFEWLGESGSDCGIVNINTSPS 489

  Fly   877 -TDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY 913
             .::...|||.|.:|.|::.|.:|..:|.:...:||.:
Mosquito   490 GAEIGGAFGGEKHTGGGRESGSDAWKQYARRSTITVNH 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	131/491 (27%)
Aldh7A1	XP_316857.3	ALDH_F7_AASADH	52..528	CDD:143448	131/493 (27%)