Protein Alignment CG8665 and aldh1l2

DIOPT Version :10

• Sequence 1: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_002938116.1
• Gene: aldh1l2 / 100127737
• XenbaseID: XB-GENE-5820495
• Length: 922
• Species: Xenopus tropicalis
• Alignment Length: 915
• Identity: 543/915 - (59%)
• Similarity: 687/915 - (75%)
• Gaps: 19/915 - (2%)

  Fly     4 KMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKG 68
            |:|:|:||||.|..:|...|....: :||||||:|||..:.|.||..|.....|||||..||.||
 Frog    22 KLRLALIGQSLFGQEVYNNLRKEGH-KIVGVFTVPDKDGKADPLAVAAEKDGTPVFKFPRWRVKG 85

  Fly    69 VALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDE 133
            .::|||:|.||||||.|||||:|:|||||:||:....|||.|||||||||||||||:||||.||:
 Frog    86 KSIPEVVEAYKSVGADLNVLPYCTQFIPMDVIDSPKNGSIIYHPSILPRHRGASAINWTLINGDK 150

  Fly   134 VAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQ 198
            .||||:|||||||||||:||.|..:||..||:||:|.|||:|||:|||..||.::|.|.||:|.|
 Frog   151 KAGFSVFWADDGLDTGPILLQRACDVEPNDTVDTLYNRFLFPEGIKAMLEAVQLIADGKAPRIGQ 215

  Fly   199 PEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSA 263
            ||.||||: .:.|.||..|....:|:.|.|::||.|.||||...:     .|:.:.|:|:.|..
 Frog   216 PEDGATYE-GIQKKENAKICWDNSAQAIHNWIRGHDKVPGAWTLI-----NEQMVTLYGSSLLD- 273

  Fly   264 GPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIK-RGTKVISASEWFKQAEDQSITDF 327
            |||..|:.:.:.|.:|...:...||::.|.||..:.||.:: ...|:|.||::|.: :|.:..:.
 Frog   274 GPVPTGQPVSVEGASKPGLVTKNGLVLFGNDGKMLTIRNLQFEDGKMIPASKYFSK-DDSATLEL 337

  Fly   328 SEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMA 389
            :|.|....|.:..|||.||.  ..:|::||||.|||.||||||||||:|:..: :.||||.|:||
 Frog   338 TEQEKAVESEIRNIWKGILSNVSVIENTTDFFKSGAASMDVVRLVEELKQKCEGLELQNEDVYMA 402

  Fly   390 PVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVN 454
            ..||||..::||.||    |...::|..:..:|..|...:::|.|.||||:|.||:..:|.:.:|
 Frog   403 TTFEEFIQMVVRKLR----GEDKEELVIDYASLNVNNMTVKMPYQCFINGQFADADNGKTYDTIN 463

  Fly   455 PTNEEVLCKVACASATDVDKAVRAAHSAF-YGSWRQITPRQRGQLMLNLADLMERNKEELATIES 518
            ||:..|:||||..|..||||||.||..|| .|.|.::..|.||:::..||||||.::|||||||:
 Frog   464 PTDGSVICKVAYCSVADVDKAVAAAKDAFENGEWGKMNARDRGRILYRLADLMEEHQEELATIEA 528

  Fly   519 VDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPW 583
            :|||||||||||||||||::.:||||||||||||:|||:|.||||..||||:|||:|||.::.||
 Frog   529 IDSGAVYTLALKTHVGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPW 593

  Fly   584 NYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVA 648
            |||||||:||.|||:|||||.::||||..||||||||||.|:||.|.||||:|||.|...||.::
 Frog   594 NYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAVKAGVPKGVINILPGSGGLVGQRLS 658

  Fly   649 DHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNK 713
            :|..:|||||||||||||.||||||.|||||.|||||||||||||.|||:||||:.||.:|:|||
 Frog   659 EHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCDLDKAVRMGMGAVYFNK 723

  Fly   714 GENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDE 778
            |||||||||||||:.|||||:.||:::::.|.|||||||||.||||||:||.:||||:|..||.|
 Frog   724 GENCIAAGRLFVEESIHDEFVTRVVEEIKKMRIGDPLDRSTDHGPQNHRAHLEKLLEYCEIGVKE 788

  Fly   779 GAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEY 843
            ||.|||||.:||. .|:|..|||||:|.|.|::|:||||||||:||||...|||.:::|||.|||
 Frog   789 GATLVYGGRKVPR-PGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGVLRRANNTEY 852

  Fly   844 GLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKC 908
            |||||||||||.||:..:::::|||||:|.|||||||||||||||||:|||||:|||:|||:||.
 Frog   853 GLASGVFTKDISKAMYVSEKLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALHEYLRTKA 917

  Fly   909 VTVEY 913
            |||||
 Frog   918 VTVEY 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886	126/201 (63%)
		FDH_Hydrolase_C	212..316	CDD:187731	34/104 (33%)
		PP-binding	336..394	CDD:425746	33/60 (55%)
		ALDH_F1L_FTFDH	428..913	CDD:143458	331/485 (68%)
aldh1l2	XP_002938116.1	FMT_core_FDH_N	23..225	CDD:187716	126/203 (62%)
		FDH_Hydrolase_C	228..327	CDD:187731	34/104 (33%)
		PP-binding	346..407	CDD:425746	33/60 (55%)
		ALDH_F1L_FTFDH	437..922	CDD:143458	331/485 (68%)