Protein Alignment Tsp39D and CD81

DIOPT Version :10

• Sequence 1: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 50/181 - (27%)
• Similarity: 92/181 - (50%)
• Gaps: 20/181 - (11%)

  Fly    55 ILMIVGAAVAVICFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFN 119
            ||:.|||.:..:.||||.||::||.|::.:|....|::|..|:..|:.|:|....:.:.::..::
Human   163 ILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYD 227

  Fly   120 STMQHYKERADYRDAWTLLQT---ELDCCGINGPNDWETVYRNSTLPAACCSVI--NLSEAKECT 179
            ..:|......|..:|..:::|   .|||||            :|||.|...||:  ||..:....
Human   228 QALQQAVVDDDANNAKAVVKTFHETLDCCG------------SSTLTALTTSVLKNNLCPSGSNI 280

  Fly   180 NTHATQHGCLQKLLEILDSKTLI--LASVVLGVAGI-QMLTILFACCLYRS 227
            .::..:..|.||:.::...|..:  :|::|:.|..| :|:..:..||..|:
Human   281 ISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRN 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspanin	9..226	CDD:459767	49/178 (28%)
		tetraspanin_LEL	131..>167	CDD:351888	11/38 (29%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	47/175 (27%)