Protein Alignment Tsp39D and CD63

DIOPT Version :9

• Sequence 1: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: NP_001244318.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 66/234 - (28%)
• Similarity: 117/234 - (50%)
• Gaps: 6/234 - (2%)

  Fly     4 GGLTCVKYLTFFCNLLF--ALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTAPIILMIVGAAVAVI 66
            ||:.|||:|.:...|.|  ...||:...||..:.|:...........:  .|::::.||..:.::
Human     5 GGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSL--LPVVIIAVGVFLFLV 67

  Fly    67 CFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERADY 131
            .|:|||||.||:.|::::||:...:|.|.|:...:||||....:.....:.|...|::|.:....
Human    68 AFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHT 132

  Fly   132 RDAWTLLQTELDCCGINGPNDWETV--YRNSTLPAACCSVINLSEAKECTNTHATQHGCLQKLLE 194
            ......:|.:..|||.....|||.:  ...:.:|.:||..:.:............:.||::|:..
Human   133 ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGG 197

  Fly   195 ILDSKTLILASVVLGVAGIQMLTILFACCLYRSFRRSYD 233
            .|....|::|:..||:|.:::|.|:|||||.:|.|..|:
Human   198 WLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspannin	8..227	CDD:278750	61/222 (27%)
		tetraspanin_LEL	104..200	CDD:239401	19/97 (20%)
CD63	NP_001244318.1	Tetraspannin	10..227	CDD:395265	58/218 (27%)
		CD63_LEL	105..203	CDD:239419	19/97 (20%)
		Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731	234..238		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1467737at2759
OrthoFinder	1	1.000	-	-		FOG0005733
OrthoInspector	1	1.000	-	-		mtm8510
orthoMCL	1	0.900	-	-		OOG6_106877
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4418
SonicParanoid	1	1.000	-	-		X3621
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.750