DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp39D and Tsp42Ed

DIOPT Version :9

Sequence 1:	NP_523612.3	Gene:	Tsp39D / 35405	FlyBaseID:	FBgn0032943	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001286152.1	Gene:	Tsp42Ed / 35613	FlyBaseID:	FBgn0029507	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	236	Identity:	69/236 - (29%)
Similarity:	119/236 - (50%)	Gaps:	20/236 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGGLTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYS----NFVSDHVWTAPIILMIVGA 61
            |..||: .|||:.|..|:||.:.|:|:...|.::......:|    .|.::.|   .||::::|.
  Fly     1 MDCGGV-FVKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGVGETFTANSV---AIIILVLGC 61

  Fly    62 AVAVICFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYK 126
            .|.::.|:|||||::|:||.:.|::::.:|:.:.::.|.:..:|.|..:.|.:|....:.....|
  Fly    62 VVFLVAFMGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLEKIVQTIWDQRK 126

  Fly   127 ERADYRDAWTLLQTELDCCGINGPNDWETVYRNSTLPAACCSVINLSEAKECTNTHA-TQHGCLQ 190
            ..|...|.   ||....|||:||..|:...|     ||:||   :......|..|.. |:..||:
  Fly   127 TDALLMDT---LQRSFKCCGLNGFADYGITY-----PASCC---DSPSNGTCALTQVMTRSSCLK 180

  Fly   191 KLLEILDSKTLILASVVLGVAGIQMLTILFACCLYRSFRRS 231
            .:....|:...|:....|||..::::..:|||||....|.|
  Fly   181 AVDSFWDTNVSIIKYAGLGVTAVELVAFIFACCLANQTRNS 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspannin	8..227	CDD:278750	64/223 (29%)
Tsp39D	NP_523612.3	tetraspanin_LEL	104..200	CDD:239401	26/96 (27%)
Tsp42Ed	NP_001286152.1	Tetraspannin	8..217	CDD:278750	64/222 (29%)
Tsp42Ed	NP_001286152.1	tetraspanin_LEL	104..189	CDD:239401	26/95 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910