DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp39D and Tspan1

DIOPT Version :9

Sequence 1:	NP_523612.3	Gene:	Tsp39D / 35405	FlyBaseID:	FBgn0032943	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001004236.1	Gene:	Tspan1 / 298436	RGDID:	1303308	Length:	241	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	59/237 - (24%)
Similarity:	103/237 - (43%)	Gaps:	26/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VKYLTFFCNLLFALTGLLIFLVGGMVQLN-------YAHYSNFVSDHVWTAPIILMIVGAAVAVI 66
            :|.:....|||..|.|..:..||..|.::       :...|:.....| .....|:..||.:.::
  Rat     7 IKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLKAFGSLSSSAMQFV-NVGYFLIAAGAVLFIL 70

  Fly    67 CFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTM------QHY 125
            .||||.||..|:.|:::.|..:.::||:.||...:...|..|     |..||.:.:      :.|
  Rat    71 GFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTT-----MAEQFLTFLVVPAIEKDY 130

  Fly   126 KERADYRDAWTLLQTELDCCGINGPNDWET---VYRNSTLPAACCSVINLSEAKE-CTNTHATQ- 185
            ..:.::...|......|.|||.|...|:.:   |..|...|..||:....|...| ||...|..
  Rat   131 GYQTEFTQVWNSTMEGLHCCGFNNYTDFNSSRFVKENKVFPPFCCANNTDSHTVEPCTEDKAKSM 195

  Fly   186 --HGCLQKLLEILDSKTLILASVVLGVAGIQMLTILFACCLY 225
              .||.:::|:.:.:..:.:..|.:|||.:::..::.:..||
  Rat   196 NVQGCFKQILQKIRTNAVTVGGVAVGVAALELAAMVVSMYLY 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspannin	8..227	CDD:278750	59/237 (25%)
Tsp39D	NP_523612.3	tetraspanin_LEL	104..200	CDD:239401	26/108 (24%)
Tspan1	NP_001004236.1	Tetraspannin	7..236	CDD:395265	57/234 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910