Protein Alignment Tsp39D and Cd37

DIOPT Version :10

• Sequence 1: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: XP_017444339.1
• Gene: Cd37 / 29185
• RGDID: 62035
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 65/262 - (24%)
• Similarity: 112/262 - (42%)
• Gaps: 48/262 - (18%)

  Fly     6 LTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVS-----DHVWTAPIILMIVGAAVAV 65
            |:.:||..|..||.|.:.|.|||..|..:.::...:.:||.     ...|:.  :|.:.|.....
  Rat    31 LSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFVSFVGLSFVPLQTWSK--VLSVSGVLTMA 93

  Fly    66 ICFLGCCGALKESSCMI-LSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERA 129
            :..|||.|||||..|:: |.|.:| :::|..:|.||:....:...|.:.::.....|:|.|:...
  Rat    94 LALLGCVGALKELRCLLGLYFGML-LLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNP 157

  Fly   130 D---YRDAWTLLQTELDCCGINGPNDW---ETVYRNST----LPAACCS--------------VI 170
            |   ..::|...|.:|.|||...|.||   :.:..|.:    :|.:|.:              :.
  Rat   158 DETAAEESWDYAQFQLRCCGWQSPRDWNKAQMLKANGSEELFVPCSCYNSTATNDSSGFDKLFLS 222

  Fly   171 NLSE----------AKEC---TNTHATQHGCLQKLLEILDSKTLILASVVLGVAGIQMLTILFAC 222
            .||.          |..|   ...|..:.||.:.|.:.|.:..:.:..:.|||..:::..:  |.
  Rat   223 QLSRLGPRAKLRQTADICALPAKAHIYREGCARSLQKWLHNNIISIVGICLGVGLLEVSGM--AL 285

  Fly   223 CL 224
            ||
  Rat   286 CL 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspanin	9..226	CDD:459767	64/259 (25%)
		tetraspanin_LEL	131..>167	CDD:351888	11/42 (26%)
Cd37	XP_017444339.1	Tetraspanin	49..>177	CDD:459767	35/130 (27%)
		CD37_CD82_like_LEL	131..266	CDD:239413	26/134 (19%)