Protein Alignment Tsp39D and TSPAN15

DIOPT Version :10

• Sequence 1: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 53/246 - (21%)
• Similarity: 105/246 - (42%)
• Gaps: 50/246 - (20%)

  Fly     9 VKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTAP-IILMIVGAAVAVICFLGCC 72
            :|:.....:.:|.|.|.|:..||...::....|....|  .:.|| |||:::|..:.::.|:|..
Human    20 LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLES--AFLAPAIILILLGVVMFMVSFIGVL 82

  Fly    73 GALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQ---IMESQFNSTMQHYKERADYRDA 134
            .:|:::..::.:|..:..:..:.|:   :.|.|..|..:|   .:.......:::|.:..|:::.
Human    83 ASLRDNLYLLQAFMYILGICLIMEL---IGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNI 144

  Fly   135 WTLLQTELDCCGINGPNDW-ETVYRNSTLPA--AC-----CSVINLSEA-----------KE--- 177
            ...:|.:..|||.....|| :..|.:.:.|.  ||     |.:.|.:|.           ||
Human   145 MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFS 209

  Fly   178 ---------CTNTHATQHGCLQKLLEILDSKTLILASVVLGVAGIQMLTIL 219
                     |||.         .::..:|:.| |:|.::||:...|.|.:|
Human   210 VQDVIYVRGCTNA---------VIIWFMDNYT-IMAGILLGILLPQFLGVL 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspanin	9..226	CDD:459767	53/246 (22%)
		tetraspanin_LEL	131..>167	CDD:351888	10/43 (23%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	29/141 (21%)
		penumbra_like_LEL	114..231	CDD:239411	23/125 (18%)