Protein Alignment Tsp39D and Cd63

DIOPT Version :9

• Sequence 1: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Sequence 2: NP_001036045.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 242
• Identity: 78/242 - (32%)
• Similarity: 129/242 - (53%)
• Gaps: 22/242 - (9%)

  Fly     4 GGLTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTA----PIILMIVGAAVA 64
            ||:.|||:|.:...|.|....:.:..:|..||:....    ...|..||    |::::.|||.:.
Mouse     5 GGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQ----AITHETTAGSLLPVVIIAVGAFLF 65

  Fly    65 VICFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERA 129
            ::.|:|||||.||:.|::::||:...:|.|.|:.:.:||||....:.......|...||:|.:
Mouse    66 LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLK-- 128

  Fly   130 DYRDAWTL--LQTELDCCGINGPNDWETV--YRNSTLPAACCSVINLSEAKECTN--THATQH-- 186
            |.:.|..|  ||.|.:|||.:...|||.:  .....:|.:||  ||::..  |.|  ..:|.|
Mouse   129 DNKTATILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCC--INITVG--CGNDFKESTIHTQ 189

  Fly   187 GCLQKLLEILDSKTLILASVVLGVAGIQMLTILFACCLYRSFRRSYD 233
            ||::.:...|....|::|:..||:|.:::|.|:|:|||.:|.|..|:
Mouse   190 GCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRSGYE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp39D	NP_523612.3	Tetraspannin	8..227	CDD:278750	73/230 (32%)
		tetraspanin_LEL	104..200	CDD:239401	30/103 (29%)
Cd63	NP_001036045.1	Tetraspannin	10..227	CDD:395265	70/226 (31%)
		CD63_LEL	105..203	CDD:239419	30/103 (29%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005733
OrthoInspector	1	1.000	-	-		otm43294
orthoMCL	1	0.900	-	-		OOG6_106877
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4418
SonicParanoid	1	1.000	-	-		X3621
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.740