Protein Alignment dimm and HAND2

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 49/171 - (28%)
• Similarity: 65/171 - (38%)
• Gaps: 49/171 - (28%)

  Fly    95 GHPS--------GCSLGGQGPSGRGRVQQASSGACPSTIAPNSTSSNSSNANGNASRRRKGALNA 151
            |||.        ..|...:..||...:..:..|..|....|       ....|....:|:|..|.
Human    49 GHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGP-------PGLGGPRPVKRRGTANR 106

  Fly   152 KERNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHIIL-SK 215
            |||.            |..|:|.||..|||.||:|..:.:||||:||.||.:||..|..::. ..
Human   107 KERR------------RTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159

  Fly   216 RNEEAAAL----------------ELNSGAVGGVLLSNLSS 240
            :|.||.|.                |||.     :|.|.:||
Human   160 QNGEAEAFKAEIKKTDVKEEKRKKELNE-----ILKSTVSS 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	22/59 (37%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		12/58 (21%)
		bHLH_TS_HAND2	100..161	CDD:381477	28/72 (39%)