DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dimm and Olig3

DIOPT Version :9

Sequence 1:	NP_001260674.1	Gene:	dimm / 35404	FlyBaseID:	FBgn0023091	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_443734.2	Gene:	Olig3 / 94222	MGIID:	2149955	Length:	273	Species:	Mus musculus

Alignment Length:	206	Identity:	69/206 - (33%)
Similarity:	97/206 - (47%)	Gaps:	36/206 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 RVQQASS--GACPSTIAPNSTSSNSSNANGNASRRR-KGALNAKERNMRRLESNERERMRMHSLN 173
            |:...||  |.....:...|.|...:.|.|.:|:.: |..|:.::....||:.|.|||.|||.||
Mouse    37 RLNSVSSTQGDMVQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLN 101

  Fly   174 DAFQSLREVIP--HVEMERRLSKIETLTLAKNYIINLTHIILSKRNEEAAALELNSGAVGGVLLS 236
            .|...||||:|  |....|:||||.||.||:|||:.||           ::||.....||.:...
Mouse   102 LAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLT-----------SSLEEMKRLVGEIYGG 155

  Fly   237 NLSSESGGPV--ASGIPANSNAAT----ICFEDTLASGGAFDCAILAATD----------GSLLN 285
            :.|:...|.|  ::|.||::..|.    ......|:||.|  .:.|:||.          .|||.
Mouse   156 HHSAFHCGTVGHSAGHPAHAANAVHPVHPILGGALSSGNA--SSPLSATSLPTIGTIRPPHSLLK 218

  Fly   286 AATVTTSPAMQ 296
            |.  :|.||:|
Mouse   219 AP--STPPALQ 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_001260674.1	HLH	154..208	CDD:238036	30/55 (55%)
Olig3	NP_443734.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..72		9/34 (26%)
Olig3	NP_443734.2	HLH	86..139	CDD:306515	30/52 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910