Protein Alignment dimm and ATOH8

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 63/267 - (23%)
• Similarity: 94/267 - (35%)
• Gaps: 92/267 - (34%)

  Fly    35 NGLSSESAEGSSRPVRRA----TRR------------TSQLSNNTYDLEMTD------------- 70
            |||.....:| ..|.|||    |.|            |:.|.:.|:.|:...
Human    21 NGLKKLKRKG-KEPARRANGYKTFRLDLEAPEPRAVATNGLRDRTHRLQPVPVPVPVPVPVAPAV 84

  Fly    71 SSSQSDDTSGGGGSSN-----------------GGGSTTNTGHPSGCSLGGQGPSG--------- 109
            ......||:|..|.|.                 |.|..|....|.... ..|.|.|
Human    85 PPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPPPAP-QSQAPGGPEAQPFREP 148

  Fly   110 --RGRVQQASSGACPSTIAP---------------------NSTSS------NSSNANGNASRRR 145
              |.|:...:..|.|:..||                     :|.||      |:...:..:.|:|
Human   149 GLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKR 213

  Fly   146 KGALNAKE------RNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNY 204
            .|...|..      :..|||.:|.|||.|:|:::.||::||:.:|.....::|||:..|.:|.||
Human   214 PGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNY 278

  Fly   205 IINLTHI 211
            |::|..:
Human   279 ILSLARL 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	23/55 (42%)
ATOH8	XP_011531441.1	bHLH_TS_ATOH8	224..291	CDD:381427	23/62 (37%)