DRSC/TRiP Functional Genomics Resources

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Protein Alignment dimm and Atoh8

DIOPT Version :9

Sequence 1:NP_001260674.1 Gene:dimm / 35404 FlyBaseID:FBgn0023091 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_722473.1 Gene:Atoh8 / 71093 MGIID:1918343 Length:322 Species:Mus musculus


Alignment Length:272 Identity:64/272 - (23%)
Similarity:101/272 - (37%) Gaps:101/272 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 NGLSSESAEGSSRPVRRAT-RRTSQLSNNTYDLEMTDSSSQSDDTSGGGGSSN------------ 86
            |||.....:| ..|||||. .:|.:|     |||..:..:....|:...|..:            
Mouse    21 NGLKKLKRKG-KEPVRRANGYKTFRL-----DLEAPELGATVSTTAATNGLRDRTQPFPIATPVP 79

  Fly    87 ---------GGGSTT------------NTGHPSGCSLGGQGP----------------------- 107
                     |||:.|            :.....|.:||..||                       
Mouse    80 ASVAPAVPPGGGTDTAREFRGIRAPEVSDARKRGFALGTVGPGLPTPPPPPASQSLAPGDPEAHS 144

  Fly   108 ----SGRGRVQQASSGACPSTIAP----------------------NSTSSNS-----SNANGNA 141
                :.|.|:...:..|.|:..||                      :|.||.|     ::.:.:|
Mouse   145 FREQALRPRILLCAPPARPTQSAPLAPPAAPQESPVRPAPPTRPGESSYSSISHVIYNNHPDSSA 209

  Fly   142 S-RRRKGALNAKE------RNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLT 199
            | |:|.|...|..      :..|||.:|.|||.|:|:::.||::||:.:|.....::|||:..|.
Mouse   210 SPRKRPGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILR 274

  Fly   200 LAKNYIINLTHI 211
            :|.|||::|..:
Mouse   275 IACNYILSLARL 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dimmNP_001260674.1 HLH 154..208 CDD:238036 22/53 (42%)
Atoh8NP_722473.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 77..96 4/18 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 101..144 5/42 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 159..221 13/61 (21%)
Basic motif, degenerate. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981 231..244 7/12 (58%)
HLH 232..283 CDD:278439 22/50 (44%)
Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981 245..283 14/37 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3898
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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