Protein Alignment dimm and NEUROD6

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_073565.2
• Gene: NEUROD6 / 63974
• HGNCID: 13804
• Length: 337
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 61/206 - (29%)
• Similarity: 80/206 - (38%)
• Gaps: 58/206 - (28%)

  Fly   140 NASRRRKGALNAK------ER-NMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIET 197
            |...||:|....|      || ..||.|:|.|||.|||.||||..:||:|:|.....::||||||
Human    71 NGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIET 135

  Fly   198 LTLAKNYIINLTHIILSKRNEEAAALELNSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFE 262
            |.||||||..|:.|:...:..:......|       |...||..:...||..:..|:.:.
Human   136 LRLAKNYIWALSEILRIGKRPDLLTFVQN-------LCKGLSQPTTNLVAGCLQLNARSF----- 188

  Fly   263 DTLASGGAFDCAILAATDGSLLNAATVTTSPAMQSIQSQAIHLQTPMEQQQQQASHLPHHQQAM- 326
             .:..||               .||..|.||                    ....:.|:|...:
Human   189 -LMGQGG---------------EAAHHTRSP--------------------YSTFYPPYHSPELT 217

  Fly   327 --HGHGHLGAS 335
              .|||.|..|
Human   218 TPPGHGTLDNS 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	33/58 (57%)
NEUROD6	NP_073565.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..82		4/10 (40%)
		Nuclear localization signal. /evidence=ECO:0000255	80..86		1/5 (20%)
		bHLH_TS_NeuroD6_ATOH2	82..151	CDD:381565	36/68 (53%)
		Neuro_bHLH	153..272	CDD:463621	21/124 (17%)