DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dimm and NEUROG1

DIOPT Version :9

Sequence 1:	NP_001260674.1	Gene:	dimm / 35404	FlyBaseID:	FBgn0023091	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_006152.2	Gene:	NEUROG1 / 4762	HGNCID:	7764	Length:	237	Species:	Homo sapiens

Alignment Length:	190	Identity:	64/190 - (33%)
Similarity:	86/190 - (45%)	Gaps:	33/190 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SGCSLGG--QGPSGRGRVQQASSGACPSTI----APN-STSSNSSNANGNAS--RRRKG------ 147
            ||..|.|  .......|:|||:|.:.|...    ||| |.:|....|..:..  |||:|
Human    18 SGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRS 82

  Fly   148 -ALNAKERNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHI 211
             ||....|..||:::|:|||.|||:||.|..:||.|:|....:.:|:|||||..|.|||..|
Human    83 EALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWAL--- 144

  Fly   212 ILSKRNEEAAALEL-NSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFEDTLASGGA 270
                    |..|.| :.|..||.....|......|...|.|:.::.|     ::..||.|
Human   145 --------AETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASDA-----ESWGSGAA 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_001260674.1	HLH	154..208	CDD:238036	27/53 (51%)
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..83		15/47 (32%)
		HLH	90..149	CDD:238036	29/69 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..209		6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910