Protein Alignment dimm and NEUROD2

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 79/269 - (29%)
• Similarity: 108/269 - (40%)
• Gaps: 82/269 - (30%)

  Fly   143 RRRKGALNAKERN-MRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYII 206
            ::||......||: :||.::|.|||.|||.||.|..:||:|:|.....::|||||||.||||||.
Human   107 KKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIW 171

  Fly   207 NLTHIILS-KR-------------------NEEAAALELNS-------GAVGGVLLSNLSSESGG 244
            .|:.|:.| ||                   |..|..|:|||       ||.|    :.....|||
Human   172 ALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADG----AGRFHGSGG 232

  Fly   245 PVAS---GIPANSNAATICFEDTLASGG----------------AFDCAILAATDGSLLNAATVT 290
            |.|.   ..|.:..|...|    .|:||                |::....||..|.
Human   233 PFAMHPYPYPCSRLAGAQC----QAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGG-------- 285

  Fly   291 TSPAMQSIQSQAIHLQTPM-----EQQQQQASHLPHHQQAMHGHGHLGASIQSQQQPSLVLNGTT 350
            .||...|.:.:. .|..|:     ...:|.:|  |.|:::.|...|..|           |.|:.
Human   286 ASPDYNSSEYEG-PLSPPLCLNGNFSLKQDSS--PDHEKSYHYSMHYSA-----------LPGSR 336

  Fly   351 SVGLGIGIG 359
            ..|.|:..|
Human   337 PTGHGLVFG 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	32/59 (54%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		7/21 (33%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	35/72 (49%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		2/5 (40%)
		Neuro_bHLH	180..310	CDD:463621	31/146 (21%)