Protein Alignment dimm and Twist1

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_035788.1
• Gene: Twist1 / 22160
• MGIID: 98872
• Length: 206
• Species: Mus musculus
• Alignment Length: 180
• Identity: 53/180 - (29%)
• Similarity: 84/180 - (46%)
• Gaps: 26/180 - (14%)

  Fly    45 SSRPVRRATRRTSQLSNNTYDLEMTDSSS-------QSDDTSGGGGSSNGGGSTTNTGHPSGCSL 102
            ||.||..|   ...|||:..:.:....:|       :.......|||:..||:|       |..:
Mouse     6 SSSPVSPA---DDSLSNSEEEPDRQQPASGKRGARKRRSSRRSAGGSAGPGGAT-------GGGI 60

  Fly   103 GG---QGPSGRGRVQQASSGACPSTIAPNSTSSNSSNANGNASRRRKGALNAKERNMRRLESNER 164
            ||   .|...:|:..:.|:|......|.........:::|..|.:     :.:|...:|:.:|.|
Mouse    61 GGGDEPGSPAQGKRGKKSAGGGGGGGAGGGGGGGGGSSSGGGSPQ-----SYEELQTQRVMANVR 120

  Fly   165 ERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHIILS 214
            ||.|..|||:||.:||::||.:..: :||||:||.||..||..|..::.|
Mouse   121 ERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQS 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	27/58 (47%)
Twist1	NP_035788.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..109		25/117 (21%)
		bHLH_TS_TWIST1	102..178	CDD:381418	29/74 (39%)
		Sufficient for transactivation activity	165..195		1/5 (20%)