DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dimm and TWIST2

DIOPT Version :9

Sequence 1:NP_001260674.1 Gene:dimm / 35404 FlyBaseID:FBgn0023091 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_001258822.1 Gene:TWIST2 / 117581 HGNCID:20670 Length:160 Species:Homo sapiens


Alignment Length:89 Identity:35/89 - (39%)
Similarity:55/89 - (61%) Gaps:7/89 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   132 SNSSNANGN---ASRRRKGALNA---KERNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMER 190
            |..|:.:|:   ..|.:||:.:|   :|...:|:.:|.|||.|..|||:||.:||::||.:..: 
Human    36 SKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD- 99

  Fly   191 RLSKIETLTLAKNYIINLTHIILS 214
            :||||:||.||..||..|..::.|
Human   100 KLSKIQTLKLAARYIDFLYQVLQS 123

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dimmNP_001260674.1 HLH 154..208 CDD:238036 25/53 (47%)
TWIST2NP_001258822.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..63 7/26 (27%)
bHLH_TS_TWIST2 51..132 CDD:381543 31/74 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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