Protein Alignment dimm and OLIG2

DIOPT Version :10

• Sequence 1: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_005797.1
• Gene: OLIG2 / 10215
• HGNCID: 9398
• Length: 323
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 98/355 - (27%)
• Similarity: 142/355 - (40%)
• Gaps: 99/355 - (27%)

  Fly    37 LSSESAEGSSRPVRRATRRTSQLSNNTYDLEMTDSSSQSDD------TSGGGGSSNGGGSTTNTG 95
            :.|:::..||||                      ||.:.||      :.|..||:..|| |.::.
Human     1 MDSDASLVSSRP----------------------SSPEPDDLFLPARSKGSSGSAFTGG-TVSSS 42

  Fly    96 HPSGCSLGGQGP--SGRGRVQQASSGACPS--------TIAPNSTSSNSSNANGNASRRRKGALN 150
            .||.|.     |  |...|....|:||.|.        ..:.:||||::|:|..:::::.|..:.
Human    43 TPSDCP-----PELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMT 102

  Fly   151 AKERNMRRLESNERERMRMHSLNDAFQSLREVIP--HVEMERRLSKIETLTLAKNYIINLTHIIL 213
            ..|....||:.|.|||.|||.||.|...||||:|  |....|:||||.||.||:|||:.||:.:
Human   103 EPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSL- 166

  Fly   214 SKRNEEAAAL--ELNSG--------AVGGVLLS-NLSSESGGPVASGIPANSNAATICFEDTLAS 267
                ||...|  |:..|        |.||:..| .|.:.:..|.|:...|:..|.........|:
Human   167 ----EEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAA 227

  Fly   268 GGAFDCAILAATDGSLLNAATVTTSPAMQSIQSQAIHLQTPMEQQQQQASHL------------- 319
            ..|...|..|.:..||..:..    |::.||:.....|::|   ....|:.|
Human   228 AAAAAAAAAAVSSASLPGSGL----PSVGSIRPPHGLLKSP---SAAAAAPLGGGGGGSGASGGF 285

  Fly   320 -----------------PHHQQAMHGHGHL 332
                             |||..:..|.|.|
Human   286 QHWGGMPCPCSMCQVPPPHHHVSAMGAGSL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	32/60 (53%)
OLIG2	NP_005797.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		33/133 (25%)
		bHLH_TS_OLIG2	95..179	CDD:381510	38/88 (43%)