DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dimm and neurog2

DIOPT Version :9

Sequence 1:	NP_001260674.1	Gene:	dimm / 35404	FlyBaseID:	FBgn0023091	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_002934289.2	Gene:	neurog2 / 100493110	XenbaseID:	XB-GENE-491040	Length:	213	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	58/197 - (29%)
Similarity:	87/197 - (44%)	Gaps:	33/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SGCSLGGQGPSGRGRVQQASSGACPSTIAPNSTS---------SNSSNANGNASRRRKGALNAKE 153
            |.||:.    |......|..|......::|.|.:         .||..:..:..|.:.|....|.
Frog    19 SPCSVS----SSHMSPAQTCSSDDEQLLSPTSPALMHLQAQEQENSPPSRRSRPRTKNGETVLKV 79

  Fly   154 RNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHII-LSKRN 217
            :..||:::|.|||.|||.||.|..|||||:|.:..:.:|:|||||..|.|||..|:..: |::..
Frog    80 KKTRRIKANNRERNRMHHLNSALDSLREVLPSLPEDAKLTKIETLRFAYNYIWALSETLRLAEHG 144

  Fly   218 EEAAALELNSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFEDTLASGGAFDCAILAATDGS 282
            ..|:.            ||.:|.:...|..|  |:.|     |.....:|.|:|..|..|::...
Frog   145 SSAST------------LSPMSVQDSSPSQS--PSWS-----CSSSPSSSCGSFSPASPASSTSD 190

  Fly   283 LL 284
            :|
Frog   191 ML 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dimm	NP_001260674.1	HLH	154..208	CDD:238036	28/53 (53%)
neurog2	XP_002934289.2	bHLH_TS_NGN2_ATOH4	74..142	CDD:381560	31/67 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010