Protein Alignment Mondo and MLX

DIOPT Version :9

• Sequence 1: NP_001163032.1
• Gene: Mondo / 35402
• FlyBaseID: FBgn0032940
• Length: 1119
• Species: Drosophila melanogaster
• Sequence 2: NP_733752.1
• Gene: MLX / 6945
• HGNCID: 11645
• Length: 298
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 80/276 - (28%)
• Similarity: 125/276 - (45%)
• Gaps: 40/276 - (14%)

  Fly   826 ANVTSP----LSVPVPTHQHSPKKS-ASLPMAVNSALHSPPL--GSKIHGIGLATAN-VGSNSLS 882
            |::.||    ||||....:.|...: |.:..|.:.....|.|  .|...|..::.|| :||.|.|
Human    41 ASLLSPKSPTLSVPRGCREDSSHPACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANSIGSTSAS 105

  Fly   883 LSP-----ESTFHESQDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQ 942
            ..|     :|.:|:.         :.|...:|.:||| |..||||||..||.|:|.|..::|..|
Human   106 SVPNTDDEDSDYHQE---------AYKESYKDRRRRA-HTQAEQKRRDAIKRGYDDLQTIVPTCQ 160

  Fly   943 LNP----NAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAP 1003
            ...    :.|||||.:|||..|:|:.|.:|:...::::..||.:...|.....:...|:.|: ..
Human   161 QQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAH-QD 224

  Fly  1004 VTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHC 1068
            ...:|.:.|..    .|::|....        |::.|..|:.:::|.||..||....|.|:::||
Human   225 NPHEGEDQVSD----QVKFNVFQG--------IMDSLFQSFNASISVASFQELSACVFSWIEEHC 277

  Fly  1069 SLIDLRPAVTNKLKYL 1084
            ....||..|...|..|
Human   278 KPQTLREIVIGVLHQL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mondo	NP_001163032.1	HLH	909..969	CDD:238036	29/63 (46%)
MLX	NP_733752.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		8/21 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..145		21/63 (33%)
		HLH	130..188	CDD:306515	27/58 (47%)
		Leucine-zipper	140..160		9/19 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910