Protein Alignment Mondo and Mlx

DIOPT Version :10

• Sequence 1: NP_610105.2
• Gene: Mondo / 35402
• FlyBaseID: FBgn0032940
• Length: 1119
• Species: Drosophila melanogaster
• Sequence 2: NP_001029284.1
• Gene: Mlx / 360631
• RGDID: 1308590
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 86/328 - (26%)
• Similarity: 131/328 - (39%)
• Gaps: 63/328 - (19%)

  Fly   776 DPMLNSTLAQLLTSNSRLQTAVANSSSS---------NSPSVSAIATTNSNSNAP---PVHYA-- 826
            ||.:.::.|.......|...|.|...|.         .||.:|.......:|:.|   .|.||
  Rat    10 DPWVKASSADAHAGEGRAGRARARRGSGRRGAPQLSPESPLLSRPRGCREDSSHPACAKVEYAYS 74

  Fly   827 -NVTSPLSVPVPTHQHSPKKSASLPMAVNSALHSPPLGSKIHGIGLATANVGSNSLSLSPESTFH 890
             |...|......||:.|....|:                          ::||.|.|..|.:
  Rat    75 DNSLDPGLFVESTHKGSVVSRAN--------------------------SIGSTSASSVPNT--- 110

  Fly   891 ESQDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQLNP----NAKLSK 951
            :.:||... ..|.|...:|.:||| |..||||||..||.|:|.|..::|..|...    :.||||
  Rat   111 DDEDSDYQ-QESYKESYKDRRRRA-HTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSK 173

  Fly   952 AAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAPVTRQGTEHVRQLY 1016
            |.:|||..|:|:.|.:|:...::::..||.:...|.....:...|:.|: .....:|.:.|..
  Rat   174 AIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAH-QDNPHEGEDQVSD-- 235

  Fly  1017 DIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHCSLIDLRPAVTNKL 1081
              .|::|....        |::.|..|:.:::|.||..||....|.|:::||....||..|...|
  Rat   236 --QVKFNVFQG--------IMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVL 290

  Fly  1082 KYL 1084
            ..|
  Rat   291 HQL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mondo	NP_610105.2	NES2-NLS_ChREBP-like	151..260	CDD:439286
		bHLHzip_MLXIP_like	910..982	CDD:381411	31/75 (41%)
Mlx	NP_001029284.1	bHLHzip_Mlx	129..205	CDD:381530	31/76 (41%)