Protein Alignment Mondo and LOC100535945

DIOPT Version :9

• Sequence 1: NP_001163032.1
• Gene: Mondo / 35402
• FlyBaseID: FBgn0032940
• Length: 1119
• Species: Drosophila melanogaster
• Sequence 2: NP_001315623.1
• Gene: LOC100535945 / 100535945
• -ID: -
• Length: 913
• Species: Danio rerio
• Alignment Length: 1163
• Identity: 311/1163 - (26%)
• Similarity: 452/1163 - (38%)
• Gaps: 381/1163 - (32%)

  Fly    46 ETGVGASASGSAEATADLLKAERESIHSGQFMVSHFEAEEAQ----------DDLEDDGEVKMLD 100
            :.|.|   .||...|        :.||||.||||...::..:          |:.:.|...|:
Zfish    33 DAGTG---FGSVRRT--------QVIHSGHFMVSSPHSDSVRRRSAALYNYYDNYDFDTANKL-- 84

  Fly   101 PEDPGLGKPGEPTNTCRDVQLYVPQTVAHFSAMDQEGDESSMSMVTSHLEIETSLTKLFKCMNLA 165
                          .|   |.|                 |...:.:..|.|:.:||:||:||.||
Zfish    85 --------------AC---QTY-----------------SFGPLSSRRLSIDPTLTRLFECMTLA 115

  Fly   166 YSQKLTSPKWNHFKGVRLRWKDKIRLNNVIWRCWHMQFIQKRRTPVCQFASPL---DVDIHSNPQ 227
            ||.||.||||..|||:||.|:|||||||.|||.|.:|:::||:.|||.|.:||   :.|.|..|:
Zfish   116 YSGKLVSPKWKSFKGLRLLWRDKIRLNNGIWRAWFIQYVEKRKNPVCGFITPLEGSEADAHGKPE 180

  Fly   228 TVVLEGKYWKRHSAVIKAEYRKWRRNYRSKATGCLTYDSKSELDFLEWSPLNDRNLMPDDWT--- 289
            .:||||.||||...|:..||.|||..|:.:     ...:|..|..|:.||::...|  :.|:
Zfish   181 AIVLEGSYWKRRIEVVIKEYHKWRIYYKKR-----LQKNKDLLSMLQKSPISRTGL--EKWSSQI 238

  Fly   290 -----------------------TDTLFSAINVPFPFPDSREIARGAGIADFIQPSLGPLQPNLD 331
                                   :||||:....|..:...|:....:. ||.|||.|.||||:||
Zfish   239 YSEPEAASEEVHMFDLDCFLSDISDTLFTMTQKPSAWSADRQNTYTSN-ADMIQPGLTPLQPSLD 302

  Fly   332 DIDISFSDLIPTTRLPPVPEEG-TDAEMLKNDEYCLSAIVGAPHTLYCNDSIMDVVNSSNNGAVN 395
            |: :...|:..:.|..|....| :|....                    :|....|.|||..:.
Zfish   303 DL-MDIPDIFMSFRGHPTEPVGFSDCSFF--------------------ESSSSAVFSSNPSSA- 345

  Fly   396 VDASMLELNTPINNVSYGEVEQRFSVARQVQQSNNDSQLLGDSGSMSGRIHGGKHFGPASANDNN 460
                   |||.:                                     ||.|
Zfish   346 -------LNTQM-------------------------------------IHTG------------ 354

  Fly   461 TNRCVINGRVAKSTQRPFRREPHNYDKAQPTMHQTNLYQQMLAEQQKNQQQQHVVVSSFQASQQQ 525
                      |..||.|...|
Zfish   355 ----------ALLTQPPLSAE-------------------------------------------- 365

  Fly   526 QLAQQQPFSAQATNAFNNQSFISSYADNYQHQQQLNVKVEPLHADVLSLLNDNAYNSIGYKPYPQ 590
              :..||.|:                      ..|.|...|.|    ::..|..:|.......|:
Zfish   366 --SLPQPSSS----------------------VNLPVPTYPRH----TINPDMTFNPNTETSDPK 402

  Fly   591 FKKSASTGTFLNVPRQTQQQQSYLQ--QEPPQMQQSLPVGMGNQQILQLTRQQQVNNTQQQQHQS 653
            ||                ....|:.  |.|..:...:|         ...:|...:||:..|...
Zfish   403 FK----------------GHPEYMSDFQHPLHLSSGMP---------SYGQQGAFSNTEMPQENP 442

  Fly   654 TVASLLQQQHQQQNHQQQQLQTAVSSATWVSPNTI-LPK-------------EIYRSNSLPLNVS 704
            ..|:.|:.:|:..:.|.:....|..:......:|| :|.             ||:..:|.   :|
Zfish   443 YPAACLKPRHRYSSGQSRTCSAATPTVITHKGSTITVPPADAQLGHGYSSVGEIFPPSSC---MS 504

  Fly   705 LNKLP-DGRQLHHEQPFAVPKYHSKSKSRVRSNSMHQQHTSVVSAAGAGSSSLGAHSCSNLLVTQ 768
            :|..| ....|||  .|:||:....:.:|    ..|:|     .:.||.            ||.:
Zfish   505 VNYQPMAAAGLHH--CFSVPQQVGGATAR----GKHKQ-----KSGGAP------------LVPR 546

  Fly   769 QMQQATSDPMLNSTLAQLLTSNSRLQTAVANSSSSNSPSVS--AIATTNSNSNAPPVHYANVTSP 831
            .|..:.:.|...|.||.||:|.|:          ...||:|  |.||.:....:        |||
Zfish   547 VMTSSVTPPSQTSCLANLLSSRSQ----------ERKPSLSFDAPATVSKGQRS--------TSP 593

  Fly   832 LS-VPVPTHQHSPKKSASLPMAVN-----SALH-SPPLGSKIHGIGLATANVGS----------- 878
            :: .|..:.:...:.|.|||....     |.|| ..||....|.:...::.:.|
Zfish   594 IAPQPKSSSREGSQISHSLPWVSGVIPPLSPLHCQTPLSGHGHSVSSQSSTISSLLTQQTALLVP 658

  Fly   879 NSLSLSPESTFHESQDSPL-----------SPTTSLKFQP-------RDTQRRAGHIHAEQKRRY 925
            .:..|||.. .|.|..|.|           |||::.:..|       |...||..||.||||||:
Zfish   659 KTEKLSPVQ-MHTSDRSSLTVSFPGSMGQTSPTSAAEKSPESKLESSRTDTRRITHISAEQKRRF 722

  Fly   926 NIKNGFDTLHALIPQLQLNPNAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSL 990
            |||.||||||:|:..|...|:.|:|||..|||.|::|.:::|||..|.::.:.||.:...||:::
Zfish   723 NIKLGFDTLHSLVTTLSSQPSIKISKATTLQKTAEYISKMQQERAQLHEEAQRLRDQILALNSAI 787

  Fly   991 THLHSILPANGAPVTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDE 1055
            ......|||.|.|:|||..:|:|:.:..|||..|:.:|||||..:|:|||..|:.|.||:||:|:
Zfish   788 NVCQQQLPATGVPITRQRFDHMREKFREYVRAQTLQNWKFWIFSIIIEPLFESFNSMVSTASVDD 852

  Fly  1056 LRRTAFLWVDQHCSLIDLRPAVTNKLKYLSMHTDIVSEPPSTLQEEVAKALQNSSGQH 1113
            |.|:...|:||||||..|||.|.:.|:.||..|.|:|: ||.:.|:..:|:.:....|
Zfish   853 LCRSTLSWLDQHCSLPTLRPTVLSSLRLLSTSTSILSD-PSLVPEQAVQAVTHGHSSH 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mondo	NP_001163032.1	HLH	909..969	CDD:238036	32/59 (54%)
LOC100535945	NP_001315623.1	HLH	709..767	CDD:238036	33/57 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5413
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D263805at33208
OrthoFinder	1	1.000	-	-		FOG0003465
OrthoInspector	1	1.000	-	-		otm24574
orthoMCL	1	0.900	-	-		OOG6_104294
Panther	1	1.100	-	-	LDO	PTHR15741
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5458
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.950