DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8671 and Fam102b

DIOPT Version :9

Sequence 1:	NP_001286124.1	Gene:	CG8671 / 35400	FlyBaseID:	FBgn0032938	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001157039.1	Gene:	Fam102b / 329739	MGIID:	3036259	Length:	370	Species:	Mus musculus

Alignment Length:	425	Identity:	149/425 - (35%)
Similarity:	197/425 - (46%)	Gaps:	138/425 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MMKKKKYKFNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCK 78
            ||||||:||.|:.:|::|..|..||.|||.|:||||||||...||||.|:.:.|.|.:.|.|.||
Mouse     1 MMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVHWRKKFSFMCK 65

  Fly    79 MSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTSRRFLLEGYDSRH-RLD 142
            |||:||||:||||..|:|:|||:|||::|.||||.|||||||||:|.|:||.||||||::: |.|
Mouse    66 MSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQD 130

  Fly   143 NSMLRVSIKMHMLSGDILFKAPTPNLKSKQSKPSIDDFSNAATGVGLQIPTATALPSIGGGSGGA 207
            ||:|:|.|.|.::|||..||.|          ||          ..:.||.|           |.
Mouse   131 NSILKVLISMQLMSGDPCFKTP----------PS----------TSMSIPIA-----------GE 164

  Fly   208 SVSLGGSGVTLGGIPGNQSLPGTRPVSTTKEEDIDNQALIAAIVTDSGLSESSESGVTLTTDNLQ 272
            |.||                          |||                   .:.|.|     |:
Mouse   165 SESL--------------------------EED-------------------RKGGET-----LK 179

  Fly   273 QHGSVVVANPISPVTQALP-QLGIIGSNNYGTTGGAIGFTGAGNATLIEMGHSRNSSNTSQMSKG 336
            .|..:.   .:|..:.::| :||                         ..||||.||..||.||.
Mouse   180 VHLGIA---DLSAKSASVPDELG-------------------------AWGHSRTSSYASQQSKV 216

  Fly   337 SGYSSFSHSQHSRQSSEGDSGHASRQNGQKGDEH-------QQCNSLRVVVAKSHHVHTHLSLST 394
            ||||:.    |||.||..:..|  |:|...|...       :.|:....:.|:.....|..:.:.
Mouse   217 SGYSTC----HSRSSSFSEFCH--RRNTSVGSTSTGIESILEPCDETEPITAEPSPDPTAAAATA 275

  Fly   395 TVEYASDEQLYQTPNATMTNSQKLAFEDFRTPMAE 429
            |...|.:|:.          |:|||    |.|:.:
Mouse   276 TTTTAKEEEA----------SEKLA----RCPVKQ 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8671	NP_001286124.1	NT-C2	22..161	CDD:287345	84/139 (60%)
Fam102b	NP_001157039.1	NT-C2	9..149	CDD:287345	84/139 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835245
Domainoid	1	1.000	175	1.000	Domainoid score	I3641
eggNOG	1	0.900	-	-		E1_28JCR
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3305
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318637at33208
OrthoFinder	1	1.000	-	-		FOG0002357
OrthoInspector	1	1.000	-	-		otm44204
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21456
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3220
SonicParanoid	1	1.000	-	-		X1553
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.890