DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8671 and FAM102B

DIOPT Version :9

Sequence 1:	NP_001286124.1	Gene:	CG8671 / 35400	FlyBaseID:	FBgn0032938	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001010883.2	Gene:	FAM102B / 284611	HGNCID:	27637	Length:	360	Species:	Homo sapiens

Alignment Length:	434	Identity:	146/434 - (33%)
Similarity:	199/434 - (45%)	Gaps:	133/434 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MMKKKKYKFNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCK 78
            ||||||:||.|:.:|::|..|..||.|||.|:||||||||...||||.|:.:.|.|.:.|.|.||
Human     1 MMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCK 65

  Fly    79 MSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTSRRFLLEGYDSRH-RLD 142
            |||:|:||:||||..|:|:|||:|||::|.||||.|||||||||:|.|:||.||||||::: |.|
Human    66 MSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQD 130

  Fly   143 NSMLRVSIKMHMLSGDILFKAPTPNLKSKQSKPSIDDFSNAATGVGLQIPTATALPSIGGGSGGA 207
            ||:|:|.|.|.::|||..||.|          ||                |:.::| |.|.|
Human   131 NSILKVLISMQLMSGDPCFKTP----------PS----------------TSMSIP-IAGES--- 165

  Fly   208 SVSLGGSGVTLGGIPGNQSLPGTRPVSTTKEEDIDNQALIAAIVTDSGLSESSESGVTLTTDNLQ 272
                                                          ..|.|..:.|.|     |:
Human   166 ----------------------------------------------ESLQEDRKGGET-----LK 179

  Fly   273 QHGSVVVANPISPVTQALP-QLGIIGSNNYGTTGGAIGFTGAGNATLIEMGHSRNSSNTSQMSKG 336
            .|..:.   .:|..:.::| :||                         ..||||.||..||.||.
Human   180 VHLGIA---DLSAKSASVPDELG-------------------------ACGHSRTSSYASQQSKV 216

  Fly   337 SGYSSFSHSQHSRQSSEGDSGHASRQNGQKGDEH-------QQCNSLRVVVAKSHHVHTHLSLST 394
            ||||:.    |||.||..:..|  |:|...|...       :.|:.:...:|:.       :|.|
Human   217 SGYSTC----HSRSSSFSELCH--RRNTSVGSTSTGVESILEPCDEIEQKIAEP-------NLDT 268

  Fly   395 T-VEYASDEQLYQTP-NATMTNSQKLAFEDFRTPMAELAAPLFQ 436
            . .|..:.|:|.:.| ......||....:|.|....::...:.|
Human   269 ADKEDTASEKLSRCPVKQDSVESQLKRVDDTRVDADDIVEKILQ 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8671	NP_001286124.1	NT-C2	22..161	CDD:287345	83/139 (60%)
FAM102B	NP_001010883.2	NT-C2	9..149	CDD:371003	83/139 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145144
Domainoid	1	1.000	179	1.000	Domainoid score	I3541
eggNOG	1	0.900	-	-		E1_28JCR
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2976
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318637at33208
OrthoFinder	1	1.000	-	-		FOG0002357
OrthoInspector	1	1.000	-	-		otm42150
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21456
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3220
SonicParanoid	1	1.000	-	-		X1553
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.890