DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k14505 and atpaf2

DIOPT Version :9

Sequence 1:	NP_001260668.1	Gene:	l(2)k14505 / 35399	FlyBaseID:	FBgn0021856	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_001076290.1	Gene:	atpaf2 / 560253	ZFINID:	ZDB-GENE-050411-18	Length:	291	Species:	Danio rerio

Alignment Length:	280	Identity:	121/280 - (43%)
Similarity:	173/280 - (61%)	Gaps:	17/280 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TNFSQCKGAASSFT-VRH------------YASPP---KRFYKKTSVLSGDSG-YEVVLDHRKLK 63
            |.|.|......||: |:|            |:|..   |:||:..|:..|:.| :|:.||.||||
Zfish    10 TKFGQAIIWPFSFSYVKHVPSLSTQLQKAKYSSATAERKKFYETVSITQGEGGLFEINLDKRKLK 74

  Fly    64 TPKGTPFIVRSEPLAIAVATEFDAQKENIERSRMHLSALCFTAIDNPNHLSKLDMVNYLLNFIAT 128
            ||.|..|.|.:|.||||||.|:|.||:.::...|||:.||.||:|||...:|..|::..|.|:.|
Zfish    75 TPSGKLFTVPNEALAIAVANEWDVQKDTLKFYTMHLTTLCNTALDNPTQRTKEQMISAALKFLET 139

  Fly   129 DTVLFQYDDEKDLQDLQVNEWDPVIAWFNQRYDTNLQKTMNITPPQVSEQDKMNVAKHFQSYSLE 193
            ||:.::.::...|.:||.||||||:.|..|||:..:..:.||..||:.|:.|....:|..|::..
Zfish   140 DTICYRVEEPPGLVELQTNEWDPVMNWIEQRYNVVIGSSSNIMGPQIPEETKETFHQHLNSFNFW 204

  Fly   194 TLHGFIFAVDTLKSIVLACAVIEQMLTVEKAVALARLEEEYQLKFWGRVEWAHDLSQQELQARLA 258
            :|.|..|.::.|||:||:.|:|::.|.||:||.|:|||||||::.||.|||.||....||:||.|
Zfish   205 SLTGLEFVINQLKSLVLSFALIDRHLNVEEAVLLSRLEEEYQIRSWGNVEWVHDYDMYELRARTA 269

  Fly   259 AAVLFVHLNCSENLVKQKII 278
            |..|||||:..:..||:||:
Zfish   270 AGALFVHLSSEKTSVKKKIL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k14505	NP_001260668.1	ATP12	39..159	CDD:284873	55/120 (46%)
atpaf2	NP_001076290.1	ATP12	49..170	CDD:284873	55/120 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589175
Domainoid	1	1.000	118	1.000	Domainoid score	I5827
eggNOG	1	0.900	-	-		E1_COG5387
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H34602
Inparanoid	1	1.050	229	1.000	Inparanoid score	I3437
OMA	1	1.010	-	-		QHG63179
OrthoDB	1	1.010	-	-		D468631at33208
OrthoFinder	1	1.000	-	-		FOG0004839
OrthoInspector	1	1.000	-	-		oto41735
orthoMCL	1	0.900	-	-		OOG6_102681
Panther	1	1.100	-	-	LDO	PTHR21013
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2042
SonicParanoid	1	1.000	-	-		X5183
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800