DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k14505 and Y116A8C.27

DIOPT Version :9

Sequence 1:	NP_001260668.1	Gene:	l(2)k14505 / 35399	FlyBaseID:	FBgn0021856	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_001255920.1	Gene:	Y116A8C.27 / 191004	WormBaseID:	WBGene00013804	Length:	269	Species:	Caenorhabditis elegans

Alignment Length:	260	Identity:	89/260 - (34%)
Similarity:	141/260 - (54%)	Gaps:	14/260 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ASSFTVRHYASPPKRFYKKTSVL------SGDSGYEVVLDHRKLKTPKGTPFIVRSEPLAIAVAT 83
            ||:.|      .||:|||:.||:      :|:..::|:||||.|||..|....:.|.|||:|:|.
Worm    17 ASALT------KPKKFYKEVSVINETDESTGNQIHKVLLDHRVLKTQGGQVLKLDSYPLALAIAE 75

  Fly    84 EFDAQKENIERSRMHLSALCFTAIDNPNHLSKLDMVNYLLNFIATDTVLFQYDDEKDLQDLQVNE 148
            |:.:|.|.::..:|.|:.|.|||.|||...:...:...:|:::..|||||...:...|...|..:
Worm    76 EWSSQDEFLQLGQMRLTGLAFTAQDNPLEQTADTISQKILDYVEGDTVLFFNTESSKLHRYQEEK 140

  Fly   149 WDPVIAWFNQRYDTNLQKTMNITPPQV-SEQDKMNVAKHFQSYSLETLHGFIFAVDTLKSIVLAC 212
            |.|:|...|......::.:.||....| ||.||..:.:..:.::...|.|..:|.:::||.|:|.
Worm   141 WAPLIKNLNNDLGIKVRPSENILDCDVASENDKEKIDRWIRQHNFPALVGLQYATESVKSFVIAY 205

  Fly   213 AVIEQMLTVEKAVALARLEEEYQLKFWGRVEWAHDLSQQELQARLAAAVLFVHLNCSENLVKQKI 277
            ..|...:..:.|:..|.||:..|.:.||.|||||.:.::||..||:||.|||:.| |.|...:.:
Worm   206 NAIRHHIDPDTAIDAATLEQRTQAETWGNVEWAHGIEREELMTRLSAACLFVYFN-SNNFTSKTV 269

Fly 278 277
Worm 270 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k14505	NP_001260668.1	ATP12	39..159	CDD:284873	45/125 (36%)
Y116A8C.27	NP_001255920.1	ATP12	25..150	CDD:284873	44/124 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163346
Domainoid	1	1.000	80	1.000	Domainoid score	I5563
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H34602
Inparanoid	1	1.050	147	1.000	Inparanoid score	I3003
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63179
OrthoDB	1	1.010	-	-		D468631at33208
OrthoFinder	1	1.000	-	-		FOG0004839
OrthoInspector	1	1.000	-	-		oto19863
orthoMCL	1	0.900	-	-		OOG6_102681
Panther	1	1.100	-	-	LDO	PTHR21013
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2042
SonicParanoid	1	1.000	-	-		X5183
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940