DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg18b and AtATG18a

DIOPT Version :9

Sequence 1:	NP_001260667.1	Gene:	Atg18b / 35396	FlyBaseID:	FBgn0032935	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_567132.4	Gene:	AtATG18a / 825452	AraportID:	AT3G62770	Length:	425	Species:	Arabidopsis thaliana

Alignment Length:	373	Identity:	109/373 - (29%)
Similarity:	178/373 - (47%)	Gaps:	47/373 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MNFNQDFTSLSVLSPTGLRLFSISSQDKVEEIFAK--DNTEQIRIVERLFNSSLVVLV-----TA 63
            ::||||....:|.:..|.|:.:.   |...|||.:  |....:.:||.||..:::.||     ..
plant    81 LSFNQDHACFAVGTDRGFRILNC---DPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPDPQ 142

  Fly    64 QKPNCLKMLHFKKKQDIC--NCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDMKILHSIENIAP 126
            ..||  |::.:...|..|  ...:.|::..||:.|.|:||.|.:.|.:::..|:|::|.||.||
plant   143 YPPN--KVMIWDDHQGRCIGELSFRSDVRSVRLRRDRIIVVLEQKIFVYNFSDLKLMHQIETIA- 204

  Fly   127 NEQGLCALSLNSHLAFPVCQ--TSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGALLATASE 189
            |.:||||:|........||.  ..|::||.:.:..||.. :.|||:.::..|.:..|.||||||.
plant   205 NPKGLCAVSQGVGSMVLVCPGLQKGQVRIEHYASKRTKF-VMAHDSRIACFALTQDGHLLATASS 268

  Fly   190 RGTVIRVFCVKNGQRVQEFRRGVSCVRIASLVFSASGDFLCASSNTETVHVFKIDTRAVETVELK 254
            :||::|:|...:|...||.|||.....|.||.||::..:|..||:..|||||.:...:...|:
plant   269 KGTLVRIFNTVDGTLRQEVRRGADRAEIYSLAFSSNAQWLAVSSDKGTVHVFGLKVNSGSQVK-- 331

  Fly   255 AIADVAAKSENSAKEAVASTAAEESCRPVASWGGMFSKAVSSLLLPTQVSEVLAQDRSFATVQLA 319
                   .|...|.:|..|:.:..    ::.:.|:..:..||             :.|.|..:|.
plant   332 -------DSSRIAPDATPSSPSSS----LSLFKGVLPRYFSS-------------EWSVAQFRLV 372

  Fly   320 QGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGGPCKLMSVHD 367
            : |.::|.|... ||...:::.. ||..|..:|....||....:..|:
plant   373 E-GTQYIAAFGH-QKNTVVILGM-DGSFYRCQFDPVNGGEMSQLEYHN 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg18b	NP_001260667.1	WD40	<9..281	CDD:225201	90/282 (32%)
		WD40 repeat	79..122	CDD:293791	13/44 (30%)
		WD40	<89..242	CDD:295369	61/154 (40%)
		WD40 repeat	130..166	CDD:293791	12/37 (32%)
		WD40 repeat	172..208	CDD:293791	14/35 (40%)
		WD40 repeat	212..257	CDD:293791	14/44 (32%)
AtATG18a	NP_567132.4	WD40	<134..320	CDD:421866	68/189 (36%)
		WD40 repeat	169..204	CDD:293791	13/34 (38%)
		WD40 repeat	209..246	CDD:293791	11/37 (30%)
		WD40 repeat	254..288	CDD:293791	15/33 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54442
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920