DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg18b and ATG18D

DIOPT Version :9

Sequence 1:	NP_001260667.1	Gene:	Atg18b / 35396	FlyBaseID:	FBgn0032935	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_191203.2	Gene:	ATG18D / 824811	AraportID:	AT3G56440	Length:	391	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	106/364 - (29%)
Similarity:	179/364 - (49%)	Gaps:	39/364 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MNFNQDFTSLSVLSPTGLRLFSISSQDKVEEIFAKDNTE-QIRIVERLFNSSLVVLV----TAQK 65
            :::|||::..:..:..|.|:::.   :..:|.|.::..: ..:|||.||.|:::.||    .:|.
plant    39 VSWNQDYSCFAAGTSHGFRIYNC---EPFKETFRRELKDGGFKIVEMLFRSNILALVGGGPNSQY 100

  Fly    66 PNCLKMLHFKKKQDIC--NCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDMKILHSIENIAPNE 128
            |: .|:|.:...|..|  ...:.|||..|::.|.|::|.|...|::::..|:::||.|||:| |.
plant   101 PS-NKVLIWDDHQGRCISEFTFRSEIRAVKLRRDRIVVVLEHKIYVYNFMDLRLLHQIENMA-NP 163

  Fly   129 QGLCALSLNSHLAFPVCQ--TSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGALLATASERG 191
            :|||.||.:.:.:...|.  ..||:|:.:.. |.....|.|||::::.:..:..|.||||||.:|
plant   164 RGLCCLSHHMNTSVLACPGIRRGEVRVEHFG-LNMVQIINAHDSNIACMTLTLDGLLLATASTKG 227

  Fly   192 TVIRVFCVKNGQRVQEFRRGVSCVRIASLVFSASGDFLCASSNTETVHVFKIDTRAVETVELKAI 256
            |:||:|...:|.|:||.||||....|.|:..|.:..:|..||:..|||:|.:..|.:..   .|.
plant   228 TLIRIFNTMDGTRLQEVRRGVDRADIYSIALSPNVQWLAVSSDKGTVHIFSLRVRVIGE---DAY 289

  Fly   257 ADVAAKSENSAKEAVASTAAEESCRPVASWGGMFSKAVSSLLLPTQ--VSEVLAQDRSFATVQLA 319
            :.....|.||.:..|:..:.......::...|:..|..||....:|  |.||        |...|
plant   290 STEHETSSNSLQPLVSPASGANPGSSLSFLRGVLPKYFSSEWSFSQFHVPEV--------TQYFA 346

  Fly   320 QGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGG 358
            ..|.::..|:..:           ||..|...|....||
plant   347 AFGAQNTIAIIGL-----------DGSFYRCNFDPVNGG 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg18b	NP_001260667.1	WD40	<9..281	CDD:225201	88/280 (31%)
		WD40 repeat	79..122	CDD:293791	13/44 (30%)
		WD40	<89..242	CDD:295369	58/154 (38%)
		WD40 repeat	130..166	CDD:293791	10/37 (27%)
		WD40 repeat	172..208	CDD:293791	15/35 (43%)
		WD40 repeat	212..257	CDD:293791	13/44 (30%)
ATG18D	NP_191203.2	WD40	33..373	CDD:225201	104/361 (29%)
		WD40 repeat	38..74	CDD:293791	7/37 (19%)
		WD40 repeat	80..121	CDD:293791	13/41 (32%)
		WD40	<91..278	CDD:295369	68/189 (36%)
		WD40 repeat	125..162	CDD:293791	14/37 (38%)
		WD40 repeat	167..202	CDD:293791	8/35 (23%)
		WD40 repeat	208..245	CDD:293791	16/36 (44%)
		WD40 repeat	253..279	CDD:293791	10/25 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54442
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920