DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8679 and F44E5.15

DIOPT Version :9

Sequence 1:	NP_610099.1	Gene:	CG8679 / 35395	FlyBaseID:	FBgn0032934	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_001254314.1	Gene:	F44E5.15 / 13187261	WormBaseID:	WBGene00206377	Length:	222	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	50/181 - (27%)
Similarity:	72/181 - (39%)	Gaps:	50/181 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   519 IDPRISRNLPGESAF-----------LE--KFGVWQRFLDSIFYIGKGKCSRPYAHLYDAMRQHT 570
            :|.:|..:.||.:|.           ||  ||   ..|:..|||:|||...|...|..:|:
Worm    48 VDEQIKLDFPGTTAHCYLLLHPTLLGLEDVKF---DNFVSYIFYVGKGTGFRSLHHFIEAL---- 105

  Fly   571 RLHQKREKDKTNRERGGGFRTLQPDVFRSPPPGDGKMGSRKLERILDIWQHGSGVVCLHVFHNIL 635
                ::|.|                     |..|.|.||     |:.||..|..:.|:.:|..:.
Worm   106 ----QKEND---------------------PYIDSKCGS-----IVSIWNSGQEIGCVKIFVGVS 140

  Fly   636 PIDAYTREASIIDALGLNHLTNIKRGDYYGPAQSWTMKQKKQLGIALLFKA 686
            ...|..:||::|.||..:.|||...|.:.|.:..|..|.|.|.|...:.||
Worm   141 STVAQIKEAAMIKALSKHDLTNKIEGSFLGLSNIWNNKDKCQYGSFCIRKA 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8679	NP_610099.1	ANK	15..133	CDD:238125
		ANK repeat	42..78	CDD:293786
		Ank_5	67..121	CDD:290568
		ANK repeat	80..111	CDD:293786
		LEM	404..447	CDD:128813
		GIY-YIG_COG3680_Meta	513..657	CDD:198401	39/150 (26%)
F44E5.15	NP_001254314.1	GIY-YIG_COG3680_Meta	<76..162	CDD:198401	32/122 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1451150at2759
OrthoFinder	1	1.000	-	-		FOG0005201
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3306
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950