| Sequence 1: | NP_610099.1 | Gene: | CG8679 / 35395 | FlyBaseID: | FBgn0032934 | Length: | 704 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_689576.6 | Gene: | ANKLE1 / 126549 | HGNCID: | 26812 | Length: | 615 | Species: | Homo sapiens |
| Alignment Length: | 759 | Identity: | 192/759 - (25%) |
|---|---|---|---|
| Similarity: | 298/759 - (39%) | Gaps: | 217/759 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 LALTLLDALEDENEADIMSMLERNSINAGIVPCDRGLAPLHYVCGMRNGGLAQRILERFLECPDL 72
Fly 73 ------DVNALCDGQTTALHIASIYGRTELVRMLLERGACADLADEDNKLPVHYAIEECHFEVLQ 131
Fly 132 LLRDHIFRERQIQKKQQQRVQVVDALTPNQPRYNHDVTSPYYINITHRRHRPQPKFPEPTEVECA 196
Fly 197 DIPPLPDEESVNLFALTEAHLTQLIQSQRQNQP-----------EDPCQPKRRTLIESWREKVER 250
Fly 251 SRARQSLFHQYDEHVEAMVDDAISQEDFNYKEHLQKKLRDEDNSKNLTEDAPN-SG-----RQVF 309
Fly 310 EMLVEQVSQAVVVEPEPEHSFFTAQGDEVDVAESSARQDEYFLQIKEAYVHTDDENGLVFYEARY 374
Fly 375 LQNRDRREPVEQTPK-------------ERKHDLESSVSTNYT-------------------LPL 407
Fly 408 DYETD-ALRRELTQLGAPVGPITKTTKRLYIKQLIKYKRNTEALLAAQKHAQDAQIR-------Y 464
Fly 465 SVELHRTLRSPEDFARINDYLPHEATSAAHFAQCGVTKKNMREGHLKQSFIYMLIDPRISRNLPG 529
Fly 530 ESAFLEKFGVWQRFLDSIFYIGKGKCSRPYAHLYDAMRQHTRLHQKREKDKTNRERGGGFRTLQP 594
Fly 595 DVFRSPPPGDGKMGSRKLERILDIWQHGSGVVCLHVFHNILPIDAYTREASIIDALGLNHLTNIK 659
Fly 660 RGDYYGPAQSWTMKQKKQLGIALLFKAMHIYLAEGESQLSPSDL 703 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG8679 | NP_610099.1 | ANK | 15..133 | CDD:238125 | 33/123 (27%) |
| ANK repeat | 42..78 | CDD:293786 | 11/41 (27%) | ||
| Ank_5 | 67..121 | CDD:290568 | 18/59 (31%) | ||
| ANK repeat | 80..111 | CDD:293786 | 10/30 (33%) | ||
| LEM | 404..447 | CDD:128813 | 15/62 (24%) | ||
| GIY-YIG_COG3680_Meta | 513..657 | CDD:198401 | 52/143 (36%) | ||
| ANKLE1 | NP_689576.6 | ANK | 23..128 | CDD:238125 | 30/114 (26%) |
| ANK 1 | 39..71 | 9/39 (23%) | |||
| ANK repeat | 75..106 | CDD:293786 | 10/30 (33%) | ||
| ANK 2 | 75..104 | 9/28 (32%) | |||
| ANK 3 | 108..137 | 9/46 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 138..210 | 18/107 (17%) | |||
| Nuclear export signal. /evidence=ECO:0000269|PubMed:27245214 | 271..280 | 2/8 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 283..315 | 4/40 (10%) | |||
| LEM_ANKL1 | 361..398 | CDD:240590 | 15/53 (28%) | ||
| GIY-YIG_COG3680_Meta | 450..565 | CDD:198401 | 52/143 (36%) | ||
| Nuclear localization signal. /evidence=ECO:0000269|PubMed:27245214 | 579..586 | 0/6 (0%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 147 | 1.000 | Domainoid score | I4529 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 200 | 1.000 | Inparanoid score | I3787 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1451150at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0005201 | |
| OrthoInspector | 1 | 1.000 | - | - | oto88306 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_107773 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR46427 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3306 |
| SonicParanoid | 1 | 1.000 | - | - | X4821 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 11.000 | |||||