Protein Alignment clumsy and GLR3.3

DIOPT Version :10

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_174978.1
• Gene: GLR3.3 / 840859
• AraportID: AT1G42540
• Length: 933
• Species: Arabidopsis thaliana
• Alignment Length: 1018
• Identity: 211/1018 - (20%)
• Similarity: 396/1018 - (38%)
• Gaps: 205/1018 - (20%)

  Fly     1 MYSLFLTHFLLIALPVLADIDRSQFM-VGSIFTSDKDESEIAFRTAVDRANILERNVELVPIVVY 64
            :::.|...||...|......::.:.: :||||:.|....::| :.|:|.|   .::|...|.::
plant     4 LWTFFFLSFLCSGLFRRTHSEKPKVVKIGSIFSFDSVIGKVA-KIAIDEA---VKDVNSNPDIL- 63

  Fly    65 ANTDDSFIMEKMVCN----------LISQGVIAIFGPSTGSSSDIIASICDTLDIPHIVYDWIPN 119
            :.|..|..|:...|:          .:.:.::.|.||.....:.:|:.:.:.|.:|.:.:
plant    64 SGTKFSVSMQNSNCSGFMGMVEALRFMEKDIVGIIGPQCSVVAHMISHMANELRVPLLSF----- 123

  Fly   120 ESIPDREHSTMT----LNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETD----KELQQLQDIL-- 174
             ::.|...|.:.    :.....:|.....:|.||..:.|:....|:..|    ..:..|.|.|
plant   124 -AVTDPVMSPLQFPYFIRTTQSDLYQMDAIASIVDFYGWKEVIAVFVDDDFGRNGVAALNDKLAS 187

  Fly   175 -------QVGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANELKML 232
                   :.|  :...|.|.:    ::....|.:|.|.....:::|...:....:.::|..|.|:
plant   188 RRLRITYKAG--LHPDTAVNK----NEIMNMLIKIMLLQPRIVVIHVYSELGFAVFKEAKYLGMM 246

  Fly   233 GE-YQSVFIPLLDTHSIDFGELSGVE--ANITTVRLMDP----SDFHVKNVVHDWEEREKREGRY 290
            |. |..:....|.| ::|.......|  ..|..|.::.|    |||             |||  :
plant   247 GNGYVWIATDWLST-NLDSSSPLPAERLETIQGVLVLRPHTPDSDF-------------KRE--F 295

  Fly   291 FKVDPNRVKSQMILLN-------DAVWLFSKGLTE------------------LGIFEELTAPDL 330
            || ...::....:.||       |:|.|.::||.:                  ||     .:.:|
plant   296 FK-RWRKMSGASLALNTYGLYAYDSVMLLARGLDKFFKDGGNISFSNHSMLNTLG-----KSGNL 354

  Fly   331 ECRRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLATWDPVNGL 395
            .......:..|:.:::.|........||::.|..:..|:......:.:...|...:..|...:||
plant   355 NLEAMTVFDGGEALLKDILGTRMVGLTGQLQFTPDRSRTRPAYDIINVAGTGVRQIGYWSNHSGL 419

  Fly   396 -----DVLNDDEESEKRVGQKLSN-----KTF------IVSS-----RLGAPFLTLREPQEGEIL 439
                 ::|...|:.......||.:     :||      :.|:     ::|.|.....:....:|.
plant   420 STVLPELLYTKEKPNMSTSPKLKHVIWPGETFTKPRGWVFSNNGKELKIGVPLRVSYKEFVSQIR 484

  Fly   440 TGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGICDLT 504
            ...:.::|:.||:......:|.:....:..|.|.    .|...::..:|..:..||.|..:.|:.
plant   485 GTENMFKGFCIDVFTAAVNLLPYAVPVKFIPYGN----GKENPSYTHMVEMITTGNFDGVVGDVA 545

  Fly   505 MTSSRRQAVDFTPPFMTLGISIL--FSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFAL 567
            :.::|.:.||||.|:...|:.::  |.|   ..:..::||.||:..:|...|..:||:.::::.|
plant   546 IVTNRTKIVDFTQPYAASGLVVVAPFKK---LNSGAWAFLRPFNRLMWAVTGCCFLFVGIVVWIL 607

  Fly   568 ARMAPDDWENPHPCKEPEE--VENIWSIMNTTWL----SIGSLMGQGCDILPKAASTRLVTGMWW 626
            .....|::..|     |:.  |..:|...:|.:.    :..|.:|            |||..:|.
plant   608 EHRTNDEFRGP-----PKRQCVTILWFSFSTMFFAHRENTVSTLG------------RLVLIIWL 655

  Fly   627 FFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDS-NFSTYQKM 690
            |..|::.:||||:|.:.||..:.::.|...|.|..:.. ..|...|.....:.|:. |.|..:
plant   656 FVVLIINSSYTASLTSILTVQQLSSPIKGIESLRERDD-PIGYQVGSFAESYLRNELNISESR-- 717

  Fly   691 WTAMESASPSVFTKTNDEGVERVQKGKNLYAFLMESTTLEYNVERKCDLVQIGGWLDYKSYGIAM 755
              .:...:|..:.|...:|   ..|| .:.|.:.|...:|..:...|....:|.......:|.|.
plant   718 --LVPLGTPEAYAKALKDG---PSKG-GVAAIVDERPYVELFLSSNCAYRIVGQEFTKSGWGFAF 776

  Fly   756 PFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPELGLENVGGVFLVL 820
            |.:||....:|.|:|:|.|.|.|..:..||.  |......|.::.   ::..|.|::..|:||:.
plant   777 PRDSPLAIDLSTAILELAENGDLQRIHDKWL--MKNACTLENAEL---ESDRLHLKSFWGLFLIC 836

  Fly   821 GLGLLSAMVLGCTEFLWNVKSVAIEEKISLKEAFKSEALFAARIWITTKPVHTSSESGSSNSSSS 885
            |:..|.|:      ||:.|:.:        ::.:|             ||...:.......:..|
plant   837 GVACLLAL------FLYFVQII--------RQLYK-------------KPTDDAIARDQQQNHDS 874

  Fly   886 SSSRSKHSFKSQGLSMKSLKSSGYQDVEASVH-SKLKKI-GSM 926
            ||.||..  ..:.||:...|       |.|.| ||.:|| |||
plant   875 SSMRSTR--LQRFLSLMDEK-------EESKHESKKRKIDGSM 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	80/433 (18%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	89/397 (22%)
GLR3.3	NP_174978.1	PBP1_GABAb_receptor_plant	30..423	CDD:380645	80/431 (19%)
		GluR_Plant	464..807	CDD:270404	85/375 (23%)