Protein Alignment clumsy and GLR1.3

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_199652.1
• Gene: GLR1.3 / 834896
• AraportID: AT5G48410
• Length: 860
• Species: Arabidopsis thaliana
• Alignment Length: 994
• Identity: 201/994 - (20%)
• Similarity: 358/994 - (36%)
• Gaps: 288/994 - (28%)

  Fly     6 LTHFLLIALPVLA---------DID---RSQFMVGSIFTSDKDESEIA----------------- 41
            |..|||:.|..::         |:|   |.|..||.:......:.:|.
plant    11 LLSFLLVLLLFISRSFASTKNDDVDGGKRVQIRVGLVLDLGSLKGKIVKNSVSMALSYFYAIHND 75

  Fly    42 FRTAVDRANILERNVELVPIVVYANTDDSFIMEKMVCNLISQGVIAIFGPSTGSSSDIIASICDT 106
            ::|   |.::..||....|::..|:..|.         |.::||.||.|.::...:.::..:.:.
plant    76 YKT---RVSVSLRNSHGEPLLALASAVDL---------LKTEGVEAIIGGNSLLEAKLLGELGEK 128

  Fly   107 LDIPHIVYDWIPNESIPDREHSTMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQ 171
            ..:|.|..|...:.|:....|   .:....|:...::|:...:..|.|.|..:|||...:.::..
plant   129 ARVPMISLDSPFSLSLSKYTH---LIQATHDSTSEAKGITSFINVFDWNSVALVYEDHDDWRESM 190

  Fly   172 DIL-------------QVGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNLLKIL 223
            .:|             :||..:|:                                :.|.::..|
plant   191 QLLVEHFHENGVRVQSKVGFTVSS--------------------------------SEDFVMGRL 223

  Fly   224 QQANELKMLGEYQSVFI----PLLDTHSIDFGELSGVEAN----ITTVRLMDPSDFHVKNVVHDW 280
            ||   ||.||  .:||:    .::.||........|:..:    |.|.:.|  :.|| :|:  |.
plant   224 QQ---LKDLG--TTVFVVHLSEVIATHLFPCARRLGLMGDGFVWILTAKTM--NSFH-ENI--DD 278

  Fly   281 EEREKREG--RYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIFEELTAPDLECRRKKPWPFGKR 343
            ..::..||  .:....|..::.|...|.   |..|..:.|    .|||...:    ...|...
plant   279 FTKQAMEGVVGFKSYIPMSIELQNFTLR---WRKSLPVEE----AELTRLSI----SGIWAHD-- 330

  Fly   344 IIEFIKARSEE-------TSTGRIDFNE---NGQRSFFTLRFMELNSDGFLDLATWDPVNGLDVL 398
             |.|..||:.|       |||...:..:   ||....|.|...:|.|:.|            :::
plant   331 -IAFALARAAEVIRMPNVTSTLLEEITKTRFNGLSGDFQLNDKKLLSNKF------------EII 382

  Fly   399 NDDEESEKRVGQKLSNKTFIVSSRLGA----------PFLTLREPQEGEIL-----------TGN 442
            |....||:|||...||.:|.....|.:          |..:.:.|:...::           |.:
plant   383 NMIGSSERRVGFLNSNGSFSNRRHLSSTHNKLETIIWPGGSAQSPKGTSLIDSDRKKLRVLVTSS 447

  Fly   443 SRY-----------------EGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQ 490
            :|:                 ||:.|::........|::.|:....:|         ..:|.:...
plant   448 NRFPRLMKVETDPVTNELIVEGFCIEVFRASISPFNYEVEYIPWLNG---------SNYDNLAYA 503

  Fly   491 LID--GNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYM 553
            |..  ...|..:.|:|:||:|...||||.||..:|:.|:..|    ...::.|..|.:.|:||
plant   504 LHSQKDKYDAAVGDITITSNRSTYVDFTLPFTEMGLGIVAVK----ERSMWVFFQPLTPDLWI-- 562

  Fly   554 GSAYLFI--SLLLFALARMAPDDWENPHPCKEPEEVENIW--SIMNTTWLSIGSLMGQGCDILPK 614
            .||:.|:  .::::.:.|            .|.:|.:..|  .|....|....:|:....:.| |
plant   563 TSAFFFVLTGVIVWLIER------------AENKEFQGSWPQQIGVVLWFGFSTLVYAHREKL-K 614

  Fly   615 AASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFF 679
            ...:|.|..:|.|..|::..||||.|.:.:|  .|....||.||        |.....||.:
plant   615 HNLSRFVVTVWVFAVLILTASYTATLTSMMT--VQQIRFNSNED--------YVGHLSGSLI--- 666

  Fly   680 RDSNFSTYQKMWTAMESA--------SPSVFTKTNDEGVE-----RVQKGKNLYAFLM---ESTT 728
              :|.:.......||.|.        :.::..||....|:     :|..|:|...|.|   :|||
plant   667 --ANVALTSSSLRAMRSLGLNSAADYAQALLNKTVSFVVDELPYLKVVLGENPTHFFMVKTQSTT 729

  Fly   729 LEYNVERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGG 793
            ..:            |::..|.:.:.        ..:|..:.||....:|.|::::|:      .
plant   730 NGF------------GFMFQKGFELV--------PNVSREISKLRTSEKLNEMEKRWF------D 768

  Fly   794 NCEKSDEDGGDTPELGLENVGGVFLVLGLGL---LSAMVLGCTEFLWNVKSVAIEEKISLKEAFK 855
            |......|....| :.|....|:|:::|:..   |:.:|:.|....|.:    :.:.:.|.:..:
plant   769 NQLPYTTDDTSNP-ITLYRFRGLFIIIGVSFAFALAVLVILCLRDKWEI----LVDNLDLSQRLR 828

  Fly   856 SEALFAARIWITTKPVHTS 874
            ...:...|      .:|||
plant   829 HFRIHFVR------SIHTS 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	80/419 (19%)
		ANF_receptor	39..379	CDD:279440	75/389 (19%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	89/432 (21%)
		Lig_chan	548..812	CDD:278489	61/283 (22%)
GLR1.3	NP_199652.1	PBP1_GABAb_receptor	43..405	CDD:107361	89/444 (20%)
		ANF_receptor	57..385	CDD:279440	79/410 (19%)
		GluR_Plant	438..767	CDD:270404	83/391 (21%)
		Lig_chan	559..798	CDD:278489	64/295 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880