Protein Alignment clumsy and GLR2.6

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 1108
• Identity: 215/1108 - (19%)
• Similarity: 384/1108 - (34%)
• Gaps: 297/1108 - (26%)

  Fly     3 SLFLTHFLLIALPVLADIDRSQFMVGSIFTSDKDESEIAFRTAVDRANILERNVELVPIVVYA-- 65
            ||| .|.|..|||:..     .|.:..:....|.:.|:   ..|....:|:.|..|..:.:.|
plant     2 SLF-NHLLSRALPLWL-----LFFINFLVLLGKSQQEV---LQVQVGIVLDTNATLAALSLRAIN 57

  Fly    66 -------NTDDSFIMEKMVCN------------------LISQGVIAIFGPSTGSSSDIIASICD 105
                   ||.:.| ..::|.|                  :..:.|:||.||.....:..:.::.:
plant    58 MSLSEFYNTHNGF-KTRIVLNIRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPFLINLGN 121

  Fly   106 TLDIPHIVYDWIPNESIPDREHSTMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKE---- 166
            ...:|.|.:.  .:..:.|...|...:....|:......::.|::||.||....:| .|.|
plant   122 QSQVPIISFS--ASSPVLDSLRSPYFIRATHDDSSQVHAISAIIESFRWREVVPIY-ADNEFGEG 183

  Fly   167 -LQQLQDILQ-VGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANEL 229
             |..|.|..| :...|...:.:......|..:..|.::........|:|..||...::...|.|:
plant   184 ILPYLVDAFQEINVRIRYRSAISVHSTDDLVKKELYKLMTMPTRVFIVHMLPDLGSRLFSIAKEI 248

  Fly   230 KML--GEYQSVFIPLLDTHSIDFGELSGVEANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFK 292
            .|:  |....|...:.|..|: .|| |.:| |:..|       ..||.              ||
plant   249 GMMTKGYVWIVTNGIADQMSV-MGE-SSLE-NMHGV-------LGVKT--------------YF- 288

  Fly   293 VDPNRVKSQMILLNDAVWLFSKGLTELGIFE---------------------------------- 323
               :|.|..|.|  :..|....|..||..||
plant   289 ---SRSKELMYL--ETRWRKRFGGEELNNFECWGYDTATALAMSIEEISSNVNMSFSQTKRNTSR 348

  Fly   324 ELTAPDLECRRKKPWPF---GKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLD 385
            :.|..||:     ...|   |.::::.:...|.:...||... :||:....|.:.:.:...|...
plant   349 DDTGTDLD-----DLSFALSGPKLLQALATVSFKGVAGRFQL-KNGKLEATTFKIVNIEESGERT 407

  Fly   386 LATWDPVNGLDVLNDDEESEKRVGQ---KLSNKTFIVSSRLGAPFL----TLREPQEGEILTGNS 443
            :..|....||       ....||.|   |:|:.    |.|| .|.:    |:..|:..|..|...
plant   408 VGFWKSKVGL-------VKSLRVNQTGIKISHS----SHRL-RPIIWPGDTIFVPKGWEFPTNAK 460

  Fly   444 RYE---------------------------GYSIDLINEIAKMLNFKFEFRM----SPDGKYGAL 477
            :..                           |:.||:.:...:.:.:...:..    :|||
plant   461 KLRIAVPKKDGFNNFVEVTKDANTNAPTITGFCIDVFDTAMRQMPYAVPYEYIPFETPDG----- 520

  Fly   478 NKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFL 542
             |...::|.:|..:..|..|..:.|.|:.::|...|||..|:...||.::...........:.||
plant   521 -KPRGSYDEMVYHVFLGEFDGAVGDTTILANRSTYVDFALPYSETGIVVVVPVKDEREKGKWVFL 584

  Fly   543 SPFSLDVWIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMNTTWLSIGSLMGQ 607
            .|.:.::|....:::|:|.::::.....|..|:..       :.:.|  .|.|..:.|..:|.
plant   585 KPLTRELWFLTAASFLYIGIMVWIFEYQASGDFRK-------QSIIN--KISNVFYFSFSTLF-- 638

  Fly   608 GCDILP-KAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMA 671
            ...:.| ::..||::..:|.|..|::..||||.|.:.||......::...:|| ..|.:..|...
plant   639 FAHMRPSESIFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDL-RNSGVNIGYQT 702

  Fly   672 GGST------MGFFRDSNFSTY---QKMWTAMESASPSVFTKTNDEGVERVQKGKNLYAFLMEST 727
            |..|      || :::|...||   |:|....       ..|:::.|::............|...
plant   703 GSFTFERLKQMG-YKESRLKTYDTPQEMHELF-------LKKSSNGGIDAAFDEVAYVKLFMAKY 759

  Fly   728 TLEYNVER---KCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWKEM 789
            ..:|.:..   |.|           .:|.|.|..||....:|..:|.:.|...:..::.||   :
plant   760 CSKYTIIEPTFKAD-----------GFGFAFPLGSPLVPDLSRQILNITEGETMKAIENKW---L 810

  Fly   790 HGGGNCEKSDEDGGDTP----ELGLENVGGVFLVLGLGLLSAMVLGCTEFLWNVKSVAIEEKISL 850
            .|..:|  .|....|:|    ....|.:..:..|:.:.||.||:: |..:
plant   811 LGEKHC--LDSTTSDSPIRLDHHSFEALFTIVFVVSMLLLLAMLV-CRRY--------------- 857

  Fly   851 KEAFKSEALFAARIWITTKPVHTSSESGSSNSSSSSSSRSKHSFKSQGL--SMKSLKSSGYQDVE 913
                                 ...|:||..|:::|.:..:..:..:|..  :|::..|....|
plant   858 ---------------------RQESKSGEINANNSPTDGNMRAPPNQPTDDNMRAPTSPPIDD-- 899

  Fly   914 ASVHSKLKKIGSMFSLKSQKTVTPP-PEIGWKLDK----STQIDVVPTSDVDQELIPEVEPHLPH 973
                               :.:.|| |.:....|:    :.:::|...::||  :|.||:|.|.|
plant   900 -------------------QVLEPPGPALNEADDQDQLLNDEVNVGDRNEVD--IIVEVDPTLVH 943

  Fly   974 RHH 976
            |.:
plant   944 RRN 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	82/441 (19%)
		ANF_receptor	39..379	CDD:279440	78/411 (19%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	83/420 (20%)
		Lig_chan	548..812	CDD:278489	57/280 (20%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	80/429 (19%)
		GluR_Plant	460..810	CDD:270404	75/389 (19%)
		Lig_chan	590..842	CDD:365843	58/287 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880