Protein Alignment clumsy and GLR2.9

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_001325277.1
• Gene: GLR2.9 / 817458
• AraportID: AT2G29100
• Length: 942
• Species: Arabidopsis thaliana
• Alignment Length: 1041
• Identity: 212/1041 - (20%)
• Similarity: 386/1041 - (37%)
• Gaps: 238/1041 - (22%)

  Fly     3 SLFLTHFLLIALPVLADIDRSQFMVGSIFTSDKDESEI---AFRTAV-----DRANILERNVELV 59
            |.|:..|||:.:. |.....|:..||.:...:...|:|   :.:.||     |..|.|.|    :
plant    11 SYFVCGFLLMGVG-LGQNQTSEIKVGVVLDLNTTFSKICLTSIKMAVSDFYADHPNYLTR----L 70

  Fly    60 PIVVYANTDDSFIMEKMVCNLI-SQGVIAIFGPSTGSSSDIIASICDTLDIPHIVYD----WIPN 119
            .:.|..:.:|:........:|| ::.|.||.||.....:|.:..:.:...:|.|.:.    .:.:
plant    71 TLHVRDSMEDTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTITFSATSPLLTS 135

  Fly   120 ESIPDREHSTMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQ---------LQDILQ 175
            ...|....:|:      |:....:.:|.|.:.|.||....:| .|.|..:         |||: :
plant   136 IKSPYFVRATI------DDSSQVRAIASIFKFFRWRRVVAIY-VDNEFGEGFMPFLFDALQDV-E 192

  Fly   176 VGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANELKMLGEYQSVFI 240
            |...:..|..:     .|:.:..|:::........::|......|::.|.|.::.|:.|   .::
plant   193 VKRSVIPPEAI-----DDEIQKELRKLMERQARVFVVHMESSLALRVFQIARDIGMMEE---GYV 249

  Fly   241 PLLD---TH---SIDFGELSGVEANITTVRLMDP-----SDFHVKNVVHDWEEREKREGRYFKVD 294
            .|:.   ||   .|:.|........:..||...|     .||.::     |:...::|....:.|
plant   250 WLMTNGMTHMMRHINNGRSLNTIEGVLGVRSHVPKSKELGDFRLR-----WKRTFEKENPSMRDD 309

  Fly   295 PNRVKSQMILLNDAVWLFSKGLTELGIFEELTAPDLECRRKKPWPFGKRIIEFIKARSEETSTGR 359
            .|..         |:|.:. .:|.|....|      :...|..|......:.  |.|::..:.|.
plant   310 LNVF---------ALWAYD-SITALAKAVE------KANTKSLWYDNGSTLS--KNRTDLGNVGV 356

  Fly   360 IDFNENGQRSFFTLRFMELNS-----DGFLD----------------LATWDPVNGLDVLNDDEE 403
            ..:..:.|::|..:||..|..     ||.|.                :..|.|.:||  ::....
plant   357 SLYGPSLQKAFSEVRFNGLAGEFKLIDGQLQSPKFEIINFVGNEERIIGFWTPRDGL--MDATSS 419

  Fly   404 SEKRVGQKL-SNKTFIVSS---------RLGAPF---------LTLREPQEGEILTGNSRYEGYS 449
            ::|.:|..: ..|:.||..         |:|.|.         :|:..      :|......||:
plant   420 NKKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKGFFDFVKVTINP------ITNKKTPTGYA 478

  Fly   450 IDLINEIAKMLNF-------KFEFRMSPDGKYGALNKV-TQTWDGIVRQLIDGNADLGICDLTMT 506
            |::.....|.|.:       .||   ||:.....:.:| .:|||.:|.            |:|:|
plant   479 IEIFEAALKELPYLVIPEYVSFE---SPNNYNNLVYQVYDKTWDAVVG------------DITIT 528

  Fly   507 SSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMA 571
            ::|....|||.||...|:|::.........|.:.||.|:||::|:..|..::||..:::......
plant   529 ANRSLYADFTLPFTESGVSMMVPVRDNENKDTWVFLEPWSLELWVTTGCFFVFIGFVVWLFEHRV 593

  Fly   572 PDDWENPHPCKEPEEVENIWSIMNTTWLSIGSLM-GQGCDILPKAASTRLVTGMWWFFALMMLNS 635
            ..|:..|     |:     :.|..:.|.|..::: ....:::...|  |.|..:|.|..|::..|
plant   594 NTDFRGP-----PQ-----YQIGTSLWFSFSTMVFAHRENVVSNLA--RFVVVVWCFVVLVLTQS 646

  Fly   636 YTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGST------MGFFRDSNFSTYQKMWTAM 694
            |||:|.:|||......::.:..|| .:::...|...|...      :||..|
plant   647 YTASLTSFLTVQSLQPTVTNVNDL-IKNRDCVGYQGGAFVKDILLGLGFHED------------- 697

  Fly   695 ESASPSVFTKTNDEGVERVQKGKNLYAFLMESTTLEYNVERKCD-LVQIGGWLDYKSYGIAMPFN 758
             ...|....|..|:.:.: .|.|.:.|...|...|:..:.:.|. .|.:........:|.|.|.|
plant   698 -QLKPFDSAKDADDLLSK-GKSKGIAAAFDEVAYLKAILSQSCSKYVMVEPTFKTGGFGFAFPKN 760

  Fly   759 SPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPE---------LGLENVG 814
            ||...:.|.|:|.|.:.....:::.:|:.:.:             |.|:         |.|.:..
plant   761 SPLTGEFSRAILNLTQNNVTQQIEDRWFPKKN-------------DCPDPMTALSSNRLNLSSFL 812

  Fly   815 GVFLVLGLGLLSAMVLGCTEFLWNVKSV------------------AIEEKISLKEAFKSEALFA 861
            |:||:.|..:..::::....||:..:..                  ..:||......||:.|:..
plant   813 GLFLIAGTAISFSLLVFVALFLYEHRHTLGDDSEDSLWRKLKFLFKIFDEKDMNSHTFKNSAIHN 877

  Fly   862 ARIWITTKPVHTSS-------ESGSSNSSSS----SSSRSKHSFKSQGLSMKSLKSSGYQDVEAS 915
            ....:|.|....|:       :|.|.|....    |.|.|:..|.:|.:..   ...|..|:|..
plant   878 ISSPMTHKTPSPSTVQITPWPQSPSQNREFELRRVSFSPSEERFTTQPIIH---HEDGESDIECR 939

  Fly   916 V 916
            |
plant   940 V 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	81/423 (19%)
		ANF_receptor	39..379	CDD:279440	71/372 (19%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	91/406 (22%)
		Lig_chan	548..812	CDD:278489	56/280 (20%)
GLR2.9	NP_001325277.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880