Protein Alignment clumsy and Ir76b

DIOPT Version :10

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 139/613 - (22%)
• Similarity: 234/613 - (38%)
• Gaps: 102/613 - (16%)

  Fly   352 SEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLATWD---PVNGLDVLNDDEESEKRVGQKLS 413
            ::...|..|...|||..|..|    ||..|.....|.:|   ||..|:.:|..:...:.:...:.
  Fly    21 NDSPPTNLIQMGENGTLSPVT----ELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIG 81

  Fly   414 NKTFIVSSRLGAPFLTLREPQEGEILTGNSRY-EGYSIDLINEIAKMLNFKFEFRMSPDGKYGAL 477
            .|...:::....|.      ...|:|...:|. .|.|..:|:.:.|..||.:|..:..|...|:.
  Fly    82 GKHLRIATLEDFPL------SYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSP 140

  Fly   478 NKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFL 542
            :...::   ::..:.....||....:...|.:|..|.::...:..|..|:..:.|.........|
  Fly   141 SDFDRS---LIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLL 202

  Fly   543 SPFSLDVWIYMGSAYLFISLLLFALA----RMAPDDWENPHPCKEPEEVENIWSIMNTTWLSIGS 603
            :||...|||.:..:.|.:..:::||.    |:..|..:.|            :|:.:..|...|:
  Fly   203 APFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTP------------YSLGHCAWFVYGA 255

  Fly   604 LMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYG 668
            ||.||..:.|.|.||||:...||.|..::.:.|||||.||||.|:.....|:..|:..::| .:.
  Fly   256 LMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK-HFV 319

  Fly   669 AMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFT-KTNDEGVERVQKGKNLYAFLME------- 725
            :|.||......|.:|.|.  .|...|...:.:||: :|||....:....||.|.|:.:
  Fly   320 SMRGGGVEYAIRTTNESL--SMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIM 382

  Fly   726 -------STTLEYNVER-KCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELK 782
                   ..|:.::.|: .|...........|....|.|..|...:.....:|.|.|.|.:..|.
  Fly   383 LYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLS 447

  Fly   783 RKWWKEMHGGGNCEKSDEDGGDTPELGLENVGGVFLVLGLGLLSAMVLGCTEFLWN-VKSVAIEE 846
            :   :.:.....|.:  :.||...:|...::...:.::..|..:|:.:..||.::. |.|
  Fly   448 K---RNLPSAEICPQ--DLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNS----- 502

  Fly   847 KISLKEAFKSEALFAARIWITTKPVHTSSESGSSNSSSSSSSRSKHSFKSQGLSMKSLKSSGYQD 911
                    :.||...||..|...|          |..|.:.||....:       :.|.|...|.
  Fly   503 --------RQEANKWARHGIGRTP----------NGQSVAPSRWLRGW-------RRLNSGHGQL 542

  Fly   912 VEASVHSKLKKIGSMFSLKSQKTVTPPP 939
            :.||.|.              :.|||||
  Fly   543 LGASTHG--------------QNVTPPP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	15/47 (32%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	92/393 (23%)
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	21/117 (18%)
		Lig_chan	209..458	CDD:459656	67/266 (25%)