Protein Alignment clumsy and Ir68a

DIOPT Version :10

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 150/820 - (18%)
• Similarity: 279/820 - (34%)
• Gaps: 273/820 - (33%)

  Fly   148 IVQSFAW-----RSFTVVYETDKELQQLQDIL---QVGEPISNPTTVKQLGPGDD-HRP------ 197
            ::|...|     |.|.|:  ||.....:.|.:   .||..:. |..|.:....|| .||
  Fly    40 LLQKILWVANVKRCFAVI--TDDLHYPIYDRIFFESVGRRVI-PFFVMRTNESDDLQRPSRQVEL 101

  Fly   198 FLKEIKLSTDNCLILHCAPDNLLKILQQANELKMLG--------EYQSVFIPLLDTHSIDFGELS 254
            |:|.||.|  :|.:      |::.||......:.||        ..|..|:.|.|
  Fly   102 FVKAIKSS--DCEL------NVITILNGWQVQRFLGYIYDNRSLNMQKKFVLLHD---------- 148

  Fly   255 GVEANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKVD----PNRVKSQMILLNDAVWLFSKG 315
                    :||.:....|:.:|..|....:::....:.:.    |..:...:::.|.|.|...||
  Fly   149 --------LRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVLVMKNIANWELGKG 205

  Fly   316 LTELGIFEELTAPDLECRRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNS 380
            |                                        .|||.|.:.....|.|...:.::.
  Fly   206 L----------------------------------------NGRILFADKTSNLFGTSLPVAISE 230

  Fly   381 DGFLDLATWDPVNGLDVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSRY 445
              .:.:..|                       :|.|                          ..:
  Fly   231 --HVPMVLW-----------------------ANAT--------------------------KSF 244

  Fly   446 EGYSIDLINEIAKMLNFKFEFRMSP-----------DG----KYGALNKVTQTWDG------IVR 489
            :|..::::|.:.|.||||..: ..|           ||    .||:.|......:|      :|.
  Fly   245 QGVEVEIMNALGKALNFKPVY-YKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVD 308

  Fly   490 QLIDGNADLGICDLTMTSSRRQAVDFTPP-------FMTLGISILFSKPPTPPTD--LFSFLSPF 545
            ::...:|...|.||.:.....:.|:.:.|       |:|          |...||  ..:|:.||
  Fly   309 EVAAHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLT----------PESSTDNSWQTFILPF 363

  Fly   546 SLDVWIYMGSAYLFISLLLFALA------------------------------------RMAPDD 574
            |..:|:.:..:...:..:.:|::                                    |:|...
  Fly   364 SAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISR 428

  Fly   575 WENPHPCKEPEEVENIWSIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTAN 639
            :.:....:.|.::.:.::  |...|:...|:......:|:....|::||.:|.:.::::.:|.|:
  Fly   429 YRSSKGDRMPRDLFDGYT--NCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRAS 491

  Fly   640 LAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMG--FFRDSNFSTYQKMWTAMESASPSVF 702
            ..|.|.|.....:|::.||| .:|.|   ..:.|:|..  ||.::|....:|:...||     ||
  Fly   492 FTAILANPAARVTIDTLEDL-LRSHI---PPSTGATENRQFFLEANDEVARKVGEKME-----VF 547

  Fly   703 TKTNDEGVERVQKGKNLY---AFLM------ESTTLEYNVERKCDLVQIGGWLDYKSYGIAMPFN 758
             ..:|:...|:.||:..|   .|.:      :.:....::.::|.|        |....:||..|
  Fly   548 -GYSDDLTSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVL--------YMPVVLAMEKN 603

  Fly   759 SPYRKQISAAVLKLGELGQLAELKRKWWKEM--HGGGNCEKSDEDGGDTPELGLENVGGVFLVLG 821
            |..:.::.|::..|.|.|.:|    ||.|:.  |.........|     ..:.::.....|:.|.
  Fly   604 SALKPRVDASIQHLAEGGLIA----KWLKDAIEHLPAEALAQQE-----ALMNIQKFWSSFVALL 659

  Fly   822 LGLLSAMVLGCTEFLWNVKSVAIEEKI------SLKEAFK 855
            :|.:.:|:....| .|:.|.:.::..:      ||...||
  Fly   660 IGYVISMLTLLAE-RWHFKHIVMKHPMYDVYNPSLYYNFK 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	50/275 (18%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	86/449 (19%)
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	59/322 (18%)