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Protein Alignment clumsy and Gria3

DIOPT Version :9

Sequence 1:	NP_001036373.1	Gene:	clumsy / 35394	FlyBaseID:	FBgn0026255	Length:	1002	Species:	Drosophila melanogaster
Sequence 2:	NP_001106213.1	Gene:	Gria3 / 29628	RGDID:	70958	Length:	888	Species:	Rattus norvegicus

Alignment Length:	859	Identity:	287/859 - (33%)
Similarity:	449/859 - (52%)	Gaps:	70/859 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VGSIFTSDKDESEIAFRTAVD----RANILERNVELVPIVVYANTDDSFIMEKMVCNLISQGVIA 87
            :|.:|..:..:...|||.||.    ..|..|:...|...|.:.::.:||.:....|:..|:||.|
  Rat    30 IGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYA 94

  Fly    88 IFGPSTGSSSDIIASICDTLDIPHIVYDWIPNESIPDREHSTMTLNVHPDNLLLSQGLAEIVQSF 152
            |||.....|.:.:.|.|..|....:      ..|.|........:.:.|   .|...:..::..:
  Rat    95 IFGFYDQMSMNTLTSFCGALHTSFV------TPSFPTDADVQFVIQMRP---ALKGAILSLLGYY 150

  Fly   153 AWRSFTVVYETDKELQQLQDILQVGEPISNPTTVKQLGPGDDHRPF---LKEIKLSTDNCLILHC 214
            .|..|..:|:|::....||.|::.....:...|.:.:|...|.:.|   ::|:....:...::.|
  Rat   151 KWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDC 215

  Fly   215 APDNLLKILQQANELKMLGEYQSVFIPLLDTHSIDFGEL-------SGVEANITTVRLMDPSDFH 272
            ..:.:..||:|   :.:||::...:..:|  .::.|.::       .|  ||||..::::..:..
  Rat   216 EVERINTILEQ---VVILGKHSRGYHYML--ANLGFTDILLERVMHGG--ANITGFQIVNNENPM 273

  Fly   273 VKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLTEL-----GIFEELTAPDLEC 332
            |:..:..|...::||....|..|  :|....|.:||:.:.::....|     .:....:|.|...
  Rat   274 VQQFIQRWVRLDEREFPEAKNAP--LKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLA 336

  Fly   333 RRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLATWD------P 391
            ....||..|..|...:|....:..||.|.|:..|:|:.:|:...|:...|......|:      |
  Rat   337 NPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVP 401

  Fly   392 VNGLDVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSRYEGYSIDLINEI 456
            .:...:.||...||        |:|.:|::.|.:|::..::..|.  |.||.|||||.:||..||
  Rat   402 FSDQQISNDSSSSE--------NRTIVVTTILESPYVMYKKNHEQ--LEGNERYEGYCVDLAYEI 456

  Fly   457 AKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMT 521
            ||.:..|::..:..||||||.:..|:.|:|:|.:|:.|.||:.:..||:|..|.:.:||:.|||:
  Rat   457 AKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMS 521

  Fly   522 LGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDW------ENPHP 580
            |||||:..||......:||||.|.:.::|:.:..||:.:|::||.::|.:|.:|      |.|..
  Rat   522 LGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRD 586

  Fly   581 CKEPEEVENIWSIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLT 645
            .:.|.:..|.:.|.|:.|.|:|:.|.|||||.|::.|.|:|.|:||||.|::::|||||||||||
  Rat   587 PQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 651

  Fly   646 NSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFTKTNDEGV 710
            ..|..:.|.||||||.|::|.||.:..|||..|||.|..:.|:|||:.|:||.|||||||..:||
  Rat   652 VERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716

  Fly   711 ERVQKGKNLYAFLMESTTLEYNVERK-CDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGE 774
            .||:|.|..:|||:|||..||..:|| ||.:::||.||.|.||:|.|..|.....::.|||||.|
  Rat   717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNE 781

  Fly   775 LGQLAELKRKWWKEMHGGGNCEKSDEDGGD-TPELGLENVGGVFLVL--GLGLLSAMVLGCTEFL 836
            .|.|.:||.|||   :..|.|.....|..| |..|.|.||.|||.:|  ||||  ||::...||.
  Rat   782 QGLLDKLKNKWW---YDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGL--AMMVALIEFC 841

  Fly   837 WNVKSVAIEEKISL 850
            :  ||.|..:::.|
  Rat   842 Y--KSRAESKRMKL 853

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.