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Protein Alignment clumsy and Gria2

DIOPT Version :9

Sequence 1:	NP_001036373.1	Gene:	clumsy / 35394	FlyBaseID:	FBgn0026255	Length:	1002	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	937	Identity:	311/937 - (33%)
Similarity:	480/937 - (51%)	Gaps:	96/937 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTHFLLIALPVL----ADIDRSQFMVGSIFTSDKDESEIAFRTAVDRANILERNVELVPIVVYAN 66
            :.|..::..|||    ..:..:...:|.:|....|:...|||..:.:.:..|  ..|.|.:....
  Rat     4 IMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE--FRLTPHIDNLE 66

  Fly    67 TDDSFIMEKMVCNLISQGVIAIFGPSTGSSSDIIASICDTLDIPHIVYDWIPNESIPDREHSTMT 131
            ..:||.:....|:..|:||.||||.....|.:.|.|.|.||.:..|      ..|.|........
  Rat    67 VANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFI------TPSFPTDGTHPFV 125

  Fly   132 LNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQDILQVGEPISNPTTVKQLG------ 190
            :.:.||   |...|..:::.:.|..|..:|::|:.|..||.:|..........|...:|
  Rat   126 IQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDK 187

  Fly   191 PGDDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANELKMLGEYQSVFIPLLDTHSIDFGELSG 255
            ..:.:|...::::|..:..:||.|..|.:..|:.|   :..:|::...:..::.......|:|..
  Rat   188 KDETYRSLFQDLELKKERRVILDCERDKVNDIVDQ---VITIGKHVKGYHYIIANLGFTDGDLLK 249

  Fly   256 VE---ANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLT 317
            ::   ||::..:::|..|..|...:..|...|::|  |.......:|....|..|||.:.::.
  Rat   250 IQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKE--YPGAHTATIKYTSALTYDAVQVMTEA-- 310

  Fly   318 ELGIFEELTAPDLECRRK-----------KPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFF 371
                |..|....:|..|:           .||..|..|...:|....|..:|.|.|::||:|..:
  Rat   311 ----FRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINY 371

  Fly   372 TLRFMELNSDGFLDLATWDPVNGLDV-LNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQE 435
            |:..|||.::|...:..|..|:.:.| |.:........|  |.|||.:|::.|.:|::.::  :.
  Rat   372 TINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSG--LENKTVVVTTILESPYVMMK--KN 432

  Fly   436 GEILTGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGI 500
            .|:|.||.|||||.:||..||||...||::..:..||||||.:..|:.|:|:|.:|:.|.||:.|
  Rat   433 HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 497

  Fly   501 CDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLF 565
            ..||:|..|.:.:||:.|||:|||||:..||......:||||.|.:.::|:.:..||:.:|::||
  Rat   498 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 562

  Fly   566 ALARMAPDDW--ENPHPCKEPEEVE--NIWSIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWW 626
            .::|.:|.:|  |.....:|.:..|  |.:.|.|:.|.|:|:.|.|||||.|::.|.|:|.|:||
  Rat   563 LVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWW 627

  Fly   627 FFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDSNFSTYQKMW 691
            ||.|::::|||||||||||..|..:.|.|||||:.|::|.||.:..|||..|||.|..:.:.|||
  Rat   628 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMW 692

  Fly   692 TAMESASPSVFTKTNDEGVERVQKGKNLYAFLMESTTLEYNVERK-CDLVQIGGWLDYKSYGIAM 755
            |.|.||.||||.:|..|||.||:|.|..||:|:|||..||..:|| ||.:::||.||.|.||||.
  Rat   693 TYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 757

  Fly   756 PFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPE----LGLENVGGV 816
            |..|.....::.|||||.|.|.|.:||.|||   :..|.|   ...|||:.|    |.|.||.||
  Rat   758 PKGSSLGNAVNLAVLKLNEQGLLDKLKNKWW---YDKGEC---GSGGGDSKEKTSALSLSNVAGV 816

  Fly   817 FLVL--GLGLLSAMVLGCTEFLWNVKSVAIEEKISLKEAFKSEALFAARIWITTKPVHTSSESGS 879
            |.:|  ||||  ||::...||                 .:||.| .|.|:.:...|.:.
  Rat   817 FYILVGGLGL--AMLVALIEF-----------------CYKSRA-EAKRMKVAKNPQNI------ 855

  Fly   880 SNSSSSSSSRSKHSFKSQGLSMKSLKS 906
             |.|||.:|::..::| :|.::..::|
  Rat   856 -NPSSSQNSQNFATYK-EGYNVYGIES 880

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.