Protein Alignment clumsy and glr-8

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 125/552 - (22%)
• Similarity: 195/552 - (35%)
• Gaps: 108/552 - (19%)

  Fly   388 TWDPVNGLDVLNDDEESEKRVGQK------------------LSN-KTFIVSSRLGAPFLTLR-- 431
            |.|| |.:..||:..||   :.:|                  ||| |.|.:|...|.   ||:
 Worm    10 TADP-NSIRTLNNILES---INEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGR---TLKMV 67

  Fly   432 ----EPQ-------EGEILTGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWD 485
                ||.       ....:|......|..::::.||.|.||..:|...:....:|  ..:..:|.
 Worm    68 VPAIEPPYVNYVNFSDAAVTDKGYGPGVVMEILKEIGKRLNLTYEILPALGSTWG--EYLNGSWT 130

  Fly   486 GIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTD-LFSFLSPFSLDV 549
            |...||:.|..||......|...|....|.|.||......|:...|.....| |.....|||.:|
 Worm   131 GAFGQLVRGEVDLLAGGAIMEYDRSVIADLTYPFQFEPTGIMIRSPEKYEDDTLLIVTEPFSWEV 195

  Fly   550 WIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMNTT-----WLSIGSLMGQGC 609
            |:...:..|...::...:..:                :..::..|..|     |:.....:.||.
 Worm   196 WVITAAVILISGVIFLVMTNI----------------IRKVYEEMTVTPFESIWVFFSIFVQQGL 244

  Fly   610 DILPKAASTRLVTGMWWFFALMMLNSYTANLAAFL----TNSRQANSINSAEDLAAQSKIKYGAM 670
            ...|::.|.|::..:||..::.:..::|.:|.|..    ||....| |:....|..|.|.:. .|
 Worm   245 PEQPRSWSCRVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQN-IDQLVRLVKQGKFEI-VM 307

  Fly   671 AGGSTMGFFRD-----SNFSTYQKMWTAMESASPSVFTKTNDEGVERVQKGKNLYAFLMESTTLE 730
            ...|   |.|.     |....|:.:|..|.......:......||..|:.... ||.|....||.
 Worm   308 DENS---FTRTEMIARSKLPVYRDLWHEMIVNHKVKYVNGIARGVAFVRANPG-YALLGPMATLN 368

  Fly   731 YNVERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNC 795
            :.....|.::.....:......|.:..||.|....|..:.::.|.|    ..:||..:.......
 Worm   369 FYAYSDCKVILFNDGILPVYLSIPLVKNSIYSPYFSTKIREMVERG----FTQKWIADYRSYVAM 429

  Fly   796 EKSDEDGGDT--PE--LGLENVGGVFLVL--GLGLLSAMVLGCTEFLWNVKSVAIEEKISLKEAF 854
            :|.:|....|  |:  |.|:...|.|.|.  |.||..|:.:|  ||::..    ..||::
 Worm   430 QKINECNSTTIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVG--EFIFKF----FREKMT----- 483

  Fly   855 KSEALFAARIWITTKP--VHTSSESGSSNSSS 884
                   .....||.|  |.|.|.:.:.||:|
 Worm   484 -------KHTKTTTVPPEVATVSANVAENSTS 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	4/7 (57%)
		ANF_receptor	39..379	CDD:279440
		PBP2_iGluR_Kainate	414..787	CDD:270432	87/401 (22%)
		Lig_chan	548..812	CDD:278489	55/281 (20%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	82/392 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770