Protein Alignment clumsy and LOC110438919

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: XP_021328141.1
• Gene: LOC110438919 / 110438919
• -ID: -
• Length: 1417
• Species: Danio rerio
• Alignment Length: 1018
• Identity: 229/1018 - (22%)
• Similarity: 395/1018 - (38%)
• Gaps: 291/1018 - (28%)

  Fly    89 FGPSTGSSSDIIASICDTLDIPHIVYDW----IPNESIPDREHSTMTLNVHPDNLLLSQGLAEIV 149
            ||||....:.::.:|.:.       |||    |.....|..:.....:....:|..:...|.|::
Zfish     5 FGPSIEQQASVMLNIMEE-------YDWYIFSIVTTYYPGYQDFVTKIRSTIENSFVGWELEEVL 62

  Fly   150 ---QSFAWRSFTVVYETDKELQQLQDILQVGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLI 211
               .|        |.:.|.::|.|...||  .|:                             ::
Zfish    63 LLDMS--------VDDGDAKIQNLLKKLQ--SPV-----------------------------IL 88

  Fly   212 LHCAPDNLLKILQQANELKMLGEYQSVFIPLLDTHSIDFGELSGVEANITTVRLMDPSDFHVKNV 276
            |:...:....|.|.|:.:.:.|...:..:|     |:..|:...:.|...|..:....|
Zfish    89 LYSTKEEANIIFQVAHSVGLTGYGYTWIVP-----SLVAGDADHIPAEFPTGMISVSYD------ 142

  Fly   277 VHDWE---EREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIFEELTAPDLECRRKKPW 338
              :|:   |...|:|           ..:|....:..:..:|...|...|...|||    :|.|.
Zfish   143 --EWDYGLEARVRDG-----------VAVIATATSTMMMDRGPHTLLKSECHGAPD----KKSPM 190

  Fly   339 PFGKRIIEFIKARSEETSTGR-IDFNENGQRSFFTLRFMELNSDGFLDLATWDPV---------- 392
            .....  |.::.....|..|| :.|:|:|.:....|..:.|:.:     ..||.|
Zfish   191 TGNNN--EVLRYLMNVTFEGRNLSFSEDGYQMHPKLVIILLDKE-----RQWDRVGKWENGSLSM 248

  Fly   393 -----------NGLDVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLR--EPQEGEIL----- 439
                       :|.:...||..|             ||:.. .|||:.:.  :|..|..:
Zfish   249 KYHVWPRFELYSGPEAREDDHLS-------------IVTLE-EAPFVIVEDVDPLSGTCMRNTVP 299

  Fly   440 ----------TGNSRY------EGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIV 488
                      |.:|..      :|:.||::.:|||.:.|.::..:..:||:|  .|:..||:|:|
Zfish   300 CRKQLKALNQTQDSAVYIKRCCKGFCIDILKKIAKNVKFTYDLYLVTNGKHG--KKINGTWNGMV 362

  Fly   489 RQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKP--PTPPTDLFSFLSPFSLDVWI 551
            .:::..||.:.:..||:...|.:.:||:.||:..|||::.|:.  ...|:   :||.|||.||||
Zfish   363 GEVVLKNAHMAVGSLTINEERSEVIDFSVPFIETGISVMVSRSNGTVSPS---AFLEPFSADVWI 424

  Fly   552 YMGSAYLFISLLLF-ALA-------------RMAPDDWENPHPCKEPEEVENIWSIMNTTWLSIG 602
            .|     |:.|||. |:|             |...|..|...|.         ::|....||..|
Zfish   425 MM-----FVMLLLVSAIAVFIFEYFSPVGYNRCLADGREAGGPS---------FTIGKAIWLLWG 475

  Fly   603 SLMGQGCDIL-PKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQS--- 663
            .:......:. |:..:::::..:|.|||::.|.|||||||||:......:.::...|...|:
Zfish   476 LVFNNSVPVQNPRGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQNPND 540

  Fly   664 ---KIKYGAMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFTKTN-DEGVERVQKGKNLYAFLM 724
               ..::|.:..|||....|::    |:.|.:.|..     |.:.| .|.:|.::.|| |.||:.
Zfish   541 FSPPFRFGTVPNGSTERNIRNN----YRDMHSYMVK-----FHQRNVVEALESLKTGK-LDAFIY 595

  Fly   725 ESTTLEYNVERK--CDLVQIGGWLDYKS--YGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKW 785
            ::..|.|...|.  |.||.||....:.|  ||||:..:|.:::|:..|:|:|...|::.||:..|
Zfish   596 DAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALW 660

  Fly   786 WKEMHGGGNC--EKSDEDGGDTPELGLENVGGVFLVLGLGLLSAMVLGCTE--FLWNVK------ 840
            ..     |.|  ||::.   .:.:|.::|:.|||.:||..:..:::....|  |.|:::
Zfish   661 LT-----GICHHEKNEV---MSSQLDVDNMAGVFYMLGAAMALSLITFIAEHVFYWHMRFCFMGV 717

  Fly   841 --------------------SVAIEEKISLKEAFKSEALFAARIWITTKPVHTSSESGSSNSSSS 885
                                .|.||:        ||.||              :|.|.:.|::.|
Zfish   718 CSGKPGFTFTISREIYSCIHGVEIED--------KSSAL--------------NSPSATMNNTHS 760

  Fly   886 SSSRSKHSFKSQGLSMKSLKSSGYQDVEASVHSKL---KKIGSMFSLKSQKTVTPPPEIGWKLDK 947
            :..|...:.|    :|.||  ||   |..|.||.|   ::..|::.:...:.     .:....|
Zfish   761 NILRLLRTAK----NMASL--SG---VNGSPHSALDFIRRESSVYDISEHRR-----SLAGHSD- 810

  Fly   948 STQIDVVPTSDVDQELIPEVEP-----HLPHRHHHHHHHRHHH 985
             .:...:|..::..:.|.|||.     ||...:.:..|:.|||
Zfish   811 -CKAPYLPDDNMFSDYISEVERTFGNLHLKDSNLYQDHYLHHH 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	58/338 (17%)
		ANF_receptor	39..379	CDD:279440	53/300 (18%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	118/423 (28%)
		Lig_chan	548..812	CDD:278489	80/291 (27%)
LOC110438919	XP_021328141.1	PBP1_iGluR_NMDA_NR2	<1..255	CDD:107373	57/330 (17%)
		PBP2_iGluR_NMDA_Nr2	267..667	CDD:270436	123/447 (28%)
		DUF4013	<389..478	CDD:315788	32/105 (30%)
		NMDAR2_C	704..1417	CDD:313729	38/187 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740